TrialAssure, a leading technology provider advancing clinical trial transparency, disclosure, and data sharing, announced the launch of its new enhanced content search and sourcing capability, a technical upgrade designed to boost accuracy, transparency, and reliability across its suite of AI-powered tools. This advancement enables a more structured way for artificial intelligence (AI) to interpret, segment, and retrieve information from source documents, enabling users to gain more precise insights and greater control over the content.

TrialAssure has introduced an integrated framework that leverages AI Large Language Models (LLMs) to process and manage content more effectively. This framework emphasizes efficient document ingestion and chunking, optimized embedding and indexing, structured information storage, and advanced AI prompt design and engineering.

These techniques replace the out-of-the-box indexing and retrieval approaches and improve the visibility and traceability of AI responses, giving users greater confidence and a more efficient approach to generating structured and regulated documents in the life sciences arena. 

This also creates a more flexible and tailored experience, allowing AI models to separate, label, and group source material with greater specificity. For instance, information used to create clinical narratives can now be isolated by individual trial participants to eliminate cross-contamination and improve document fidelity.

“Giving the pharma and biotech industry clarity into how AI reaches its outputs was a technical challenge at first, but it is our usability promise,” said Zach Weingarden, MS, Director of AI Technology & Applications, TrialAssure. “We are focused on raising the standard for how AI can operate transparently in highly regulated environments like life sciences.”

Less Prompting and Increased Visibility into AI Reasoning

With the integrated approach to source management, TrialAssure product users can expect more accurate results with less time spent on prompt refinement. Instead of engineering detailed prompts to achieve clarity, users have the option now to simply point to the exact source or file that they wish the model to reference and pull from a pre-built library of prompts. This feature improves output quality across use cases, especially when working with sensitive regulatory documents.

TrialAssure’s new architecture also helps resolve the common concern that AI outputs feel like a “black box,” said in numerous industry conversations. Now, users can view the specific sentences and document sections the AI used to generate each response. An upcoming visual user experience update will illustrate the exact areas within a source document that contributed to the generated text to provide a clear audit trail and increase trust from internal and external teams from AI outputs.

Shared Benefits Across all TrialAssure Tools

The enhanced indexing feature was built into LINK AI® to support document drafting, and it is already being applied across TrialAssure ANONYMIZE® and TrialAssure REGISTRY®. For reference, this feature helps in the following ways:

• LINK AI®: Improves traceability and relevance of AI-generated paragraphs, helping streamline submission-quality clinical document creation.
• ANONYMIZE®: Enhances source targeting during redaction and anonymization tasks, improving alignment between context and masking decisions.
• REGISTRY®: Supports better mapping of fields and reference data, helping users validate where the model is pulling from and refine clinical trial results disclosure more precisely.

“This advancement shows the true depth of talent across TrialAssure’s product and technical teams,” said Prasad M. Koppolu, COO, TrialAssure. “We take great pride in building solutions that anticipate real-world needs in clinical research and the transparency field at large. By blending AI advancement with the right level of human knowledge, our team continues to push boundaries globally.”

To learn more about TrialAssure’s AI capabilities or request a demonstration of enhanced indexing, visit www.trialassure.com.