The Latest

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    Kendall Davis/BioPharma Dive
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    Tracker

    10 clinical trials to watch in the second half of 2026

    The biotechnology sector’s upswing accelerated in the first half. Positive results from anticipated trials in lung cancer, Alzheimer’s and multiple autoimmune conditions could add to the momentum.

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    istockphoto.com / Vadym Pastukh

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    Sponsored by Premier Research

    Regulatory operations: The overlooked half of submission readiness

    Submission readiness extends beyond content. Early regulatory operations planning supports a compliant, high-quality application.

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    News roundup

    Silence cashes in on ‘differentiated’ data; UK reaffirms support for childhood vaccines

    Some analysts believe Silence’s polycythemia vera drug could be superior to a closely watched Takeda medicine. Elsewhere, the FDA spurned a radiopharmaceutical and AbCellera shares climbed to levels not seen since 2023.

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    Q&A // Gene editing

    Scribe’s Benjamin Oakes on a rare IPO and bringing CRISPR to the masses

    The CEO spoke with BioPharma Dive about convincing investors to buy into the first gene editing IPO in more than two years. 

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    Startup launches

    Ex-Legend CEO takes helm at biotech startup scouring the globe for drugs

    Ying Huang is now running K2 Therapeutics, which has licensed multiple prospects from China-based biotechs and is searching for more “high-potential” medicines.

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    Emerging biotech

    Vaderis hauls in $152M to test an AKT-targeting drug

    The startup is one of at least a few young companies zeroing in on the rare bleeding disorder, hereditary hemorrhagic telangiectasia, with a more precise AKT blocker.

  • a photo of Epicrispr Biotechnologies CEO Amber Salzman standing in a white lab coat facing the camera with a woman behind her to her left in a white lab coat with black glasses holding a tube and syringe, and a woman in a white labcoat behind to the right facing the right touching lab tools.
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    Permission granted by Epicrispr Biotechnologies
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    Emerging biotech

    Epicrispr lands $90M to advance epigenetic editing drug for rare muscle disease

    The startup has completed enrollment of an early-stage study testing a first-of-its-kind treatment for facioscapulohumeral muscular dystrophy, a disease targeted by many other drugmakers.

  • A sign for Jazz Pharmaceuticals is displayed at the ASCO annual meeting in Chicago on June 2, 2018.
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    Jacob Bell/BioPharma Dive
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    Jazz to buy rare epilepsy drugmaker in potentially $1.3B deal

    Actio Biosciences, which will receive $820 million up front in the deal, adds to a major upswing in private biotech buyouts seen throughout this year.

  • Europe's JUPITER supercomputer. Big pharma companies are racing to use AI and supercomputing in drug R&D
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    Sascha Schuermann/Getty Images via Getty Images
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    Why Big Pharma is chasing the industry’s most-powerful supercomputer

    Bristol Myers Squibb is the latest major drugmaker to tap Nvidia for more computing power, betting that larger models and AI agents can speed drug discovery.

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    Alamy
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    Pain drugs

    Latigo IPO raises nearly $350M for pain drug development

    The company could rival Vertex and Lilly in the burgeoning market for non-opioid, ion-channel-blocking pain drugs. Its offering also adds to a recent and significant uptick in large biotech IPOs.

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    Deep Dive // IPO window

    Biotech IPOs are the industry’s lifeblood. Track how they’re performing.

    Drug startups have banked $6 billion in IPOs so far in 2026, more than the combined amount raised by this point in the previous four years.

    Updated Aug. 7, 2026
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    Emerging biotech

    Alkeus, an unorthodox eye drug startup, acquired by Tarsus for up to $800M

    Alkeus brought to late-stage testing a Stargardt disease therapy that former executive chairman and Vertex founder Josh Boger once called, “if it works, the most perfect drug I’ve ever seen.” 

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    News roundup

    ‘Significant’ demand for Revolution drug; Intellia pinpoints liver toxicity culprit

    Early indicators from a compassionate use plan led analysts to hike projections for daraxonrasib. Elsewhere, Intellia believes it’s answered a key safety question and Arrowhead moved to catch a rival.

  • A sign for the Food And Drug Administration is seen outside of the headquarters on July 20, 2020 in White Oak, Maryland.
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    Sarah Silbiger via Getty Images
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    Takeda approval ushers in new wave of sleep drugs

    An FDA nod mostly clears the way for Orzeyful to enter, by Wall Street estimates, a multibillion-dollar market for drugs that boost “orexin” proteins.

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    Mario Guti via Getty Images
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    Replimune rebounds to win FDA approval of melanoma drug

    The accelerated clearance follows two earlier rejections and the support of an advisory panel that disputed the arguments of FDA scientists.

  • A cooler for an organ transplant sits on a cart in an operating room, as a hospital staffer works behind.
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    Sean Gallup via Getty Images
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    Emerging biotech

    With $263M, LifeMine unearths a new drug for organ transplants

    Led by serial biotech entrepreneur Greg Verdine, the startup mined fungi genomes to find a safer alternative to the drugs widely used to prevent the body from rejecting transplanted organs. 

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    Permission granted by HI-Bio
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    IPO window

    Cardiac drug developer Braveheart banks more than $382M in IPO

    Braveheart’s offering was the largest among four biotech IPOs that collectively raised more than $1 billion from public investors last week.

    Updated Aug. 6, 2026
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    Spencer Platt via Getty Images
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    Earnings roundup: Gilead’s ‘uncertain’ future, Pfizer’s crossroads and Merck’s PCSK9 launch

    Some analysts see warning signs in crucial drug launches from Gilead and Merck, while an important trial readout could change Pfizer’s growth trajectory.

  • A Moderna logo is displayed on a building in Cambridge, Massachusetts, on Sept. 5, 2024.
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    Jacob Bell/BioPharma Dive
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    Vaccines

    FDA approves Moderna’s mRNA flu vaccine

    The clearance paves the way for the first preventive flu shot based on mRNA technology and completes a dramatic regulatory turnaround.

    FDA
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    Finn Gomez / Staff via Getty Images
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    Vaccines

    Erica Schwartz confirmed as next CDC director

    Schwartz will step into an agency that has been without a permanent leader for almost a year amid RFK Jr.’s tumultuous tenure as HHS chief. 

    FDA
  • An AstraZeneca logo stands atop an office building in Shanghai, China.
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    Robert Way via Getty Images
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    An AstraZeneca-Bristol Myers megamerger? Wall Street isn’t thrilled.

    In fact, the former lost tens of billions of dollars in market value following reports of a potential tie-up between the pharmaceutical giants.

  • Glucagon-like peptide 1 (GLP1, 7-36) molecule The glucagon like peptide-1 receptor has a strong effect on the management of type 2 diabetes mellitus.
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    Obesity drugs

    Lilly climbs, Novo falls as obesity drug battle intensifies

    A research disappointment and a miss on Wegovy pill sales hurt Novo, while Lilly’s injectable franchise once again surpassed analyst expectations.

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    IPO window

    Attovia adds to biotech IPO momentum with $289M offering

    The startup is the 12th drug company to bank at least $250 million in an IPO this year, nearly matching totals last seen during the sector’s pandemic peak, according to BioPharma Dive data.

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    China competition

    A COPD drug from China draws $115M in venture funding

    Expedition Therapeutics, which has raised nearly $300 million to date, is studying a drug it believes to have notable advantages over other COPD treatments either in development or on the market.

  • A photo of Vertex Pharmaceuticals' Boston headquarters.
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    Courtesy of Vertex Pharmaceuticals
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    Vertex’s biggest overhang: a rival 50 times smaller

    Despite another strong earnings report, analysts warned that upcoming cystic fibrosis data from Sionna Therapeutics "looms large" over Vertex.

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    Pfizer expands multibillion-dollar cost-cutting plan

    Hatched three years ago, the restructuring is now expected to deliver $1 billion in new cost reductions and save Pfizer another $1.5 billion by streamlining drug production.