The Latest
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China competition
Drugs from China are reshaping biotech. Track the licensing deals here.
Pfizer’s obesity-focused pact with YaoPharma is its second large licensing deal with a China-based drugmaker this year, following an earlier, multibillion-dollar alliance with 3SBio.
Updated 22 hours ago -
Sponsored by Aptar Digital Health
How digital companion apps unlock value across the drug lifecycle
Where companion apps unlock value across the full drug lifecycle, from Pre-Rx to Post-Rx.
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Emerging biotech
Mirum gains a hepatitis D drug in $620M buyout of startup Bluejay
The deal, which includes another $200 million in potential payouts, hands the California biotech a candidate in late-stage testing for the most severe form of viral hepatitis.
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News roundup
Dyne to seek Duchenne drug approval; Kymera, Wave and Structure shares soar
Dyne is readying a competitor to Sarepta’s Exondys 51. Elsewhere, a pair of obesity drugs showed promise and Kymera’s protein-degrading medicine displayed “biologic-like or better efficacy,” according to one analyst.
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The top biopharma conferences in 2026
Medical meetings often feature important clinical trial results, making them barometers of biotech and pharma companies’ research progress. Here’s a list of conferences to watch next year.
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Vertex CRISPR therapy hits early goal in children with blood disorders
Casgevy, now a "national priority" drug, helped kids with sickle cell and beta thalassemia, results which may help toward a label expansion and stronger commercial uptake.
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Vaccines
RFK Jr.’s hand-picked panel questions childhood vaccine schedule
After weakening an endorsement for the hepatitis B vaccine, ACIP began debating the merits of the protocol used to inoculate U.S. children against many infectious diseases.
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Hemophilia gene therapies are struggling on the market, even as innovation soars
The business case for hemophilia gene therapy still isn’t adding up due to persistent market barriers.
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Deep Dive
Biotech’s M&A outlook is uncertain. Track the deals that are happening here.
Mirum Pharmaceuticals is paying $250 million in cash and $370 million in stock for startup Bluejay Therapeutics, which is developing a treatment for chronic hepatitis D infections.
Updated Dec. 8, 2025 -
Vaccines
‘Discredited’ CDC panel weakens endorsement for newborns’ hepatitis B shot
After initially delaying a vote, ACIP backed a softer stance that dissenting members warned would cause harm to children in the future.
Updated Dec. 5, 2025 -
Vaccines
12 former FDA chiefs blast Prasad’s move to toughen vaccine standards
In an article published in NEJM, nearly all living ex-FDA commissioners lambasted the CBER head’s plans to use a probe into COVID vaccine safety to upend longstanding regulatory protocols.
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Tracey Beth Høeg, top Makary deputy, named head of FDA drug office
Høeg, a COVID-19 vaccine critic who’s been serving as a special assistant to the commissioner, will be the fifth person this year to run CDER amid heightening scrutiny of the agency.
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News roundup
Praxis soars higher; Bristol Myers’ CAR-T therapy wins broader use
Praxis shares climbed another 40% on a pair of positive updates on two different drugs. Elsewhere, Bristol Myers’ Breyanzi was cleared for its fifth cancer indication and AstraZeneca expanded a rare disease deal.
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Emerging biotech
An Arch-backed biotech raises $53M to fight neurodegeneration
SciNeuro Pharmaceuticals represents the latest in a string of Arch investments directed at the nervous system, a notoriously challenging area of drug development.
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UniQure slides further on outlook for Huntington’s gene therapy
Finalized minutes from a late-October meeting with the FDA confirm the agency doesn't see the data collected so far as enough to support an approval filing.
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Capricor soars on positive results for Duchenne cell therapy
Shares quadrupled now that the company appears on track to reverse an earlier FDA rejection of what could be the first treatment for heart-related complications of Duchenne.
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Deep Dive // Emerging biotech
Biotech startups are built on venture capital. Track funding rounds here.
Three biotech startups, led by “molecular glue” specialist Triana Biomedicines, raised more than $240 million combined in a trio of financing rounds announced over the course of two days.
Updated Dec. 4, 2025 -
After finding ‘irregularities,’ Bristol Myers to extend key trial of Cobenfy in Alzheimer’s psychosis
Data from the "ADEPT-2" study, which analysts had hoped would arrive before year's end, are now expected sometime in 2026.
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Pharvaris’ pill succeeds in late-stage trial for rare swelling disorder
Phase 3 data could make the Dutch biotech's drug competitive in the increasingly crowded market of hereditary angioedema treatments.
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Richard Pazdur, FDA drug czar, to retire from agency
Weeks after being named head of CDER, Pazdur has submitted paperwork to step down at the end of the month, exacerbating what’s already been a turbulent year at the FDA.
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FDA details plan to scale back animal tests for some antibody drugs
The draft guidance issued Tuesday comes as regulators and policymakers have looked for ways to aid U.S. drugmakers amid fast progress by their China-based counterparts.
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UK agrees to boost drug prices to dodge US pharma tariffs
A deal announced Monday will see the U.K. temporarily sidestep levies on Britain-originated drugs by loosening rules that restrain prices for new medicines.
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Emerging biotech
With $130M, Protego pushes forward a new type of amyloidosis drug
The startup’s lead prospect stabilizes abnormal proteins in patients with amyloid “light chain” amyloidosis, an approach that could represent a step forward compared to current therapies.
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Eli Lilly becomes first drugmaker to hit $1 trillion in market value
The pharmaceutical company’s success developing medicines for obesity has swelled its worth to levels associated with tech titans like Apple and Google and dwarfed that of its drugmaking peers.
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News roundup
Janux sinks on ‘overreaction’ to prostate cancer data; RFK Jr. replaces ACIP chair
Janux’s “masked” T cell engager had a lower response rate than reported last year. Elsewhere, Lilly dropped Zepbound’s price and ACIP named a new chairman days before a key vaccine meeting.
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Gene editing
Regeneron inks gene editing deal with startup Tessera
The big biotech, which has made genetic medicine a focus in recent years, is paying Tessera $150 million for rights to a potential one-and-done treatment for alpha-1 antitrypsin deficiency.