The Latest

  • An illustration for BioPharma Dive's deals database
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    Adeline Kon/BioPharma Dive
    Deep Dive

    Biotech M&A is picking back up. Here are the latest deals.

    Thirty-nine biotech companies have been bought so far this year in deals worth above $50 million, representing a combined value of nearly $43 billion.

    Updated Nov. 14, 2022
  • Medical researcher using microscope to evaluate a sample in a laboratory wearing sterile equipment
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    DC Studio/Stock.adobe.com

    Sponsored by Cardinal Health

    Navigate the complexities of cell and gene therapies

    See how the effective use of CMC expertise helped guide a biopharma company’s development of a CGT product.

  • A photo of a sign showing the Food and Drug Administration logo
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    Sarah Silbiger via Getty Images

    Spectrum to lay off R&D staff after FDA drug rejection

    The company will cut its R&D workforce by 75% and discontinue development of its experimental lung cancer drug poziotinib.

  • A picture from chest-up of Bernie Sanders speaking to reporters. The top of the US capitol building is visible behind him.
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    Anna Moneymaker/Getty Images via Getty Images

    Sanders poised to lead Senate health committee

    The longtime pharma critic is set to become chair of the HELP Committee, a post that holds significant power in directing congressional efforts on healthcare issues.

  • Blood smear on microscopic film shows the malaria parasite Plasmodium falciparum.
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    Md Ariful Islam via Getty Images

    Novartis, research group to advance new kind of malaria drug into late-stage test

    The Swiss pharma and the Medicines for Malaria Venture plan to start a Phase 3 trial of a non-artemisinin combination treatment next year.

  • Street signs for the intersection of Wall St. and Broad St., with the stripes of an American flag in the background.
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    Michael Santiago/Getty Images via Getty Images

    Biotech ObsEva sells drug rights to forestall funding crunch

    In an effort to extend its cash runway and keep its stock listing, ObsEva is offloading rights to an experimental preterm labor drug in a deal with Xoma.

  • A thumbnail illustration for BioPharma Dive's IPO tracker
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    Adeline Kon/BioPharma Dive
    Deep Dive

    After a record run, fewer biotechs are going public. Here’s how they’re performing.

    Just 20 drugmakers have priced an initial public offering this year, less than one-fifth last year’s total of 104, according to BioPharma Dive data.

    Updated Nov. 18, 2022
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    Novo Nordisk

    Novo Nordisk to boost drug manufacturing in Denmark

    The Danish drugmaker has invested heavily in expanding its production capacity for oral and injectable drugs. A new $744 million project is the latest investment.

  • A building showing a logo of Teva Pharmaceutical
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    Courtesy of Teva Pharmaceutical

    Teva taps Sandoz veteran to take over CEO post from Schultz

    Richard Francis will take over for the retiring Kåre Schultz on Jan. 1. He’ll face major challenges at Teva, including opioid settlements, biosimilar launches and reducing the company’s debt.

  • A wall showing a Merck & Co. logo in Kenilworth, New Jersey
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    Courtesy of Merck & Co.

    Merck to buy blood cancer biotech Imago for $1.35B

    The deal is Merck’s second notable acquisition in the past year and a half, part of a strategy to diversify its pipeline beyond top-selling immunotherapy Keytruda.

  • Scientists working in an R&D laboratory
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    Courtesy of Merck KGaA

    Merck KGaA outlines plan to rev up drug R&D

    The German company aims to, on average, launch a new medicine or major treatment indication every 18 months in a bid to boost its pharma business.

  • A picture of the street sign stating "Wall Street." American flags drape over a nearby building
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    Kena Betancur via Getty Images
    Deep Dive

    Health tech companies weigh funding options amid weak IPO market

    Healthcare technology companies are delaying initial share sales and searching for new sources of cash. Experts don’t expect a quick recovery.

  • Portrait of Gideon Bollag, Opna Bio's CEO.
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    Permission granted by Opna Bio

    Cancer drugmaker Plexxikon gets new life as Opna Bio

    Eight months after Daiichi Sankyo shuttered the San Francisco Bay Area subsidiary, Plexxikon’s former CEO is resuscitating its drug research under a new name.

  • An illustration of a herpes simplex virus
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    Dr_Microbe via Getty Images

    Replay reveals second gene therapy spinout, debuting new biotech Telaria

    Telaria is the second spinout in Replay’s “hub-and-spoke” model, and will focus on developing a gene therapy for recessive dystrophic epidermolysis bullosa.

  • A sign for the Food And Drug Administration is seen outside of the headquarters on July 20, 2020 in White Oak, Maryland.
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    Sarah Silbiger via Getty Images

    First-of-its-kind Type 1 diabetes drug wins FDA approval

    Provention Bio’s teplizumab is meant to prevent the onset of Type 1 diabetes. To be sold as Tzield, the drug will cost $193,900 for a typical full regimen. 

    FDA
  • FDA approves Rezvoglar as second ‘interchangeable’ insulin biosimilar

    Eli Lilly’s long-acting copycat drug, first approved in late 2021, now has a designation that will allow pharmacists to swap it for Sanofi’s Lantus.

    FDA
  • A 3D visualization of Laronde's endless RNA, or eRNA
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    Permission granted by Laronde

    Former Rubius CEO to lead buzzy Flagship startup

    Pablo Cagnoni was appointed CEO at the RNA drug startup Laronde days after departing Rubius, a once high-flying biotech that’s now laid off nearly all its employees and is seeking a sale. 

  • A photo of an Editas Medicine scientist in the lab.
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    Permission granted by Editas Medicine
    CRISPR gene editing

    Editas to seek partner for CRISPR medicine after lackluster study results

    While the biotech will not develop the gene editing therapy further on its own, CEO Gilmore O’Neill claimed the data are still a meaningful demonstration of what CRISPR can accomplish. 

  • A photo of a sign showing the Food and Drug Administration logo
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    Sarah Silbiger via Getty Images

    FDA panel votes in favor of Ardelyx’s once-rejected kidney disease drug

    The recommendation represents a surprising turnaround for Ardelyx’s drug, which the FDA put before an advisory committee only after the biotech appealed its rejection last year.

    FDA
  • A photo of Regeneron's Tarrytown, NY headquarters.
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    Regeneron

    Regeneron teams up with CytomX to develop dual-targeting cancer drugs

    Regeneron will pay CytomX $30 million to try to create bispecific antibody drugs that are safer and have a wider reach than existing treatments.  

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    Spencer Platt via Getty Images

    Pfizer, BioNTech start study testing next COVID-19 vaccine

    The new candidate is meant to provide broader immunity over a longer period of time and is part of the companies’ strategy to stay ahead of a shifting coronavirus threat.

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    monsitj via Getty Images

    Biotechs reveal layoffs, research revamps in third quarter earnings

    Tricida, Harpoon, Freeline and three other small drug developers last week announced plans to cut staff or to reprioritize their drug development.

  • Xavier Becerra sits on a couch onstage at HLTH.
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    Rebecca Pifer/BioPharma Dive

    Divided Congress after midterms will allow HHS to execute on policy priorities, Becerra says

    The agency is focused on implementing drug price negotiation in Medicare and surprise billing regulations, according to the secretary.

  • An illustration showing swollen neurons with lamellar inclusions due to accumulation of gangliosides in lysosomes.
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    Dr_Microbe, iStock via Getty Images

    Freeline cuts back as it continues search for gene therapy partner

    The U.K. biotech will sell its German unit and lay off staff to save cash as it focuses on therapies for Gaucher and Fabry diseases.

  • Q&A // Emerging biotech

    Eli Lilly’s Julie Gilmore on finding up-and-coming companies and backing small biotechs

    Only a small fraction of the companies Lilly evaluates get into its incubator, according to Gilmore. Here’s how the big pharma selects them.

  • Portrait of John Mulligan, chief executive officer of Bonum.
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    Permission granted by Bonum Therapeutics

    After $250M Roche buyout, a startup plans a second strike with fresh funding

    Backed by the same investors and team as an immunotherapy biotech Roche bought in September, Bonum Therapeutics plans to develop “conditionally” active cancer medicines.