Pharma
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Trump administration
Novo, Lilly cut deal with Trump to lower prices of obesity drugs
The agreement will make Wegovy and Zepbound available to some Medicare enrollees for $245 per month, and starter doses of pill versions, once approved, for $149 monthly.
By Jonathan Gardner • Nov. 6, 2025 -
J&J brain drug acquired in $14.6B buyout cleared for broader use
Caplyta, which J&J got in its acquisition of Intra-Cellular Therapies, netted a clearance in major depressive disorder that’s key to achieving the $5 billion in annualized sales the company expects.
By Kristin Jensen • Nov. 6, 2025 -
Explore the Trendline➔
National Institute on Aging. (2017). "Beta-Amyloid Plaques and Tau in the Brain" [Image]. Retrieved from Flickr.
TrendlineAlzheimer's disease
Many companies hope to follow in the footsteps of Biogen, Eisai and Eli Lilly by developing new therapies for the debilitating disease, which affects tens of millions of people and costs healthcare systems hundreds of billions of dollars each year.
By BioPharma Dive staff -
Obesity drugs
FTC signals scrutiny of Novo’s bid for Metsera
Without taking a firm position, the antitrust agency said Novo’s two-step deal structure may illegally sidestep requirements for a premerger review.
By Jonathan Gardner • Nov. 5, 2025 -
Novo narrows sales outlook as GLP-1 price cuts loom
Ahead of a reported White House deal meant to lower the cost of obesity drugs like Wegovy, Novo said “intensifying competition and pricing pressure” led it to lower its yearly sales projections.
By Kristin Jensen • Nov. 5, 2025 -
Blackstone pays Merck $700M to buy into ADC drug royalties
The deal hands Blackstone a piece of the potential future sales of an antibody-drug conjugate that could soon challenge marketed medicines from AstraZeneca and Gilead.
By Delilah Alvarado • Nov. 4, 2025 -
Pain drugs
Lilly quietly cuts a pain drug from its pipeline
The drug, which Lilly in-licensed four years ago and is designed to inhibit a protein known as P2X7, did not meet the company’s "high internal bar for success," a spokesperson said.
By Jacob Bell • Oct. 31, 2025 -
Earnings roundup: Alnylam’s down day, Neurocrine’s head scratch and Biogen’s ‘low quality’ win
Alnylam and Neurocrine shares tumbled despite upbeat sales reports. Elsewhere, Biogen is dealing with what one analyst called “lackluster” appeal and Bristol Myers’ prized schizophrenia drug again underwhelmed.
By Jacob Bell , Ben Fidler • Oct. 30, 2025 -
Obesity drugs
Lilly hikes revenue forecasts on booming obesity drug sales
Tirzepatide, which Lilly sells as Mounjaro for diabetes and Zepbound for obesity, topped $10 billion in the third-quarter, officially becoming the world’s best-selling drug.
By Kristin Jensen • Oct. 30, 2025 -
Obesity drugs
Novo tops Pfizer with $6.5B bid for Metsera
The offer sparked a bidding war between the two large pharmas over the obesity drug specialist, with Pfizer alleging Novo’s offer is “illusory” and “structured in a way to circumvent antitrust laws.”
By Jonathan Gardner • Updated Oct. 30, 2025 -
Merck kidney cancer drug succeeds in two large trials
The results could help expand use of Welireg, one of the medicines Merck is counting on to drive revenue growth when its top-selling immunotherapy Keytruda loses patent protection.
By Jonathan Gardner • Oct. 28, 2025 -
Novartis’ $12B Avidity deal shows a willingness to take big swings in neuroscience
A 46% premium paid for RNA candidates reflects what the pharma giant has sought to do for the last few years: aim at technology that fits into its own expertise.
By Michael Gibney • Oct. 28, 2025 -
Bayer receives FDA approval for non-hormonal menopause therapy
Clearance of Lynkuet provides a new alternative to hormone-based treatment for hot flashes and sets up a market battle with Astellas Pharma’s Veozah.
By Delilah Alvarado • Oct. 27, 2025 -
Sponsored by Walgreens
Community pharmacies and BioPharma: Advancing whole-patient care together
As healthcare grows more complex, community pharmacies can help simplify and coordinate patient care.
Oct. 27, 2025 -
Novartis to acquire Avidity in $12B bet on RNA drugs for neuromuscular disease
The deal, which Novartis expects can “unlock multibillion-dollar opportunities” in the years ahead, hands the company a group of medicines for multiple forms of muscular dystrophy.
By Ben Fidler • Oct. 26, 2025 -
Vaccines
Sanofi says ‘soft’ start to fall immunizations slowed vaccine sales
The French pharma’s overall vaccine sales declined 8% in the quarter, with a key driver being slower-than-usual uptake of flu shots in the U.S.
By Delilah Alvarado • Oct. 24, 2025 -
FDA clears return of GSK’s once-withdrawn multiple myeloma drug
The new approval completes a surprise turnaround for Blenrep, which was initially cleared in 2020 but pulled from the market only two years later.
By Ben Fidler • Oct. 23, 2025 -
Sanofi drug acquired in buyout succeeds in rare disease trial
The drug’s success in a Phase 2 study in alpha-1 antitrypsin deficiency “validates” Sanofi’s 2024 acquisition of Inhibrx, according to one analyst.
By Delilah Alvarado • Oct. 22, 2025 -
Top RFK aide lashes out against healthcare industry for profiting off of illness
Calley Means stopped short of accusing hospitals, insurers and drug companies from actively working to keep Americans sick, but said it was an "economic fact" that the companies benefit financially when people are ill.
By Susanna Vogel • Oct. 22, 2025 -
China competition
Takeda stakes more than $11B on cancer drugs from China
The Japanese pharma is licensing up to three next-generation cancer drugs from Innovent Biologics in a deal it believes to be “transformative” for its oncology portfolio.
By Ben Fidler • Oct. 22, 2025 -
News roundup
Iambic partners with Jazz; Merck breaks ground on $3B plant
The biotechs will assess a combination of two drugs against HER2-positive breast cancer. Elsewhere, Merck unveiled the latest piece of its more than $70 billion domestic manufacturing investment.
By BioPharma Dive staff • Oct. 21, 2025 -
Novo’s main shareholder pushes out more than half of company’s board
The Novo Foundation chair said the current board of the Wegovy maker, which is already dealing with layoffs and a CEO change, was too slow to react to obesity market shifts.
By Jonathan Gardner • Oct. 21, 2025 -
Sponsored by Panalgo
From weeks to minutes: How generative AI transforms pharma data and ROI
GenAI is changing how pharma teams work — making data accessible, transparent, and actionable.
By Niyati Parikh, VP, Product Readiness, Panalgo • Oct. 20, 2025 -
Roche pill delays tumor progression in closely watched breast cancer study
Results presented at the European Society for Medical Oncology meeting could help separate Roche’s medicine from similar hormone-degrading drugs for breast tumors.
By Jonathan Gardner • Oct. 18, 2025 -
J&J claims success in study testing earlier Tecvayli use in multiple myeloma
The result marks a potential advance for dual-targeting antibody drugs like Tecvayli, which are currently relegated to later-line settings for the persistent blood cancer.
By Jonathan Gardner • Oct. 16, 2025 -
Novartis confirms drug’s benefits in rare kidney disease as competitors loom
The findings position Fabhalta to secure a standard approval in IgA nephropathy — a crowded area of drug research — at a time when newer types of medicines are quickly advancing.
By Kristin Jensen • Oct. 16, 2025