Novartis' MS hopes expand after positive trial

An experimental drug for secondary progressive MS showed promise in a late-stage trial, setting up a potential successor to Novartis' Gilenya. 

By Suzanne Elvidge • Sept. 19, 2016

Novo's Victoza follow-on showing heart benefits

Strengthening evidence for semaglutide could help Novo compete with Eli Lilly's Trulicity, which has performed well over the first six months of the year. 

By Lisa LaMotta • Sept. 16, 2016

Explore the Trendline➔

Neuroscience drug development

Enthusiasm is running higher among drugmakers and investors for neuroscience drug development, buoyed by recent approvals of new Alzheimer’s, ALS and depression medicines.

By BioPharma Dive staff

Novavax short on options after vaccine fails trial

Shares in the Maryland-based company collapsed on news of the Phase 3 miss, dropping over 80% and erasing nearly $2 billion in market capitalization. 

By Ned Pagliarulo • Sept. 16, 2016

Takeda partners with PRA on drug development

About 300 Takeda employees have the option to move downstream to new positions at PRA in the U.S. and Europe. 

By Suzanne Elvidge • Sept. 15, 2016

Pfizer, Merck ready diabetes combos

The big pharmas announced positive results for their SGLT2 inhibitor in combination with other classes. 

By Lisa LaMotta • Sept. 15, 2016

AcelRx stock jumps after trial success

Positive results from a third and final Phase 3 trial of AcelRx's opioid painkiller clear the way for an NDA by the end of the year. 

By Ned Pagliarulo • Sept. 15, 2016

Roche bolsters evidence for MS drug Ocrevus

New post-hoc data showed Ocrevus helped better control relapsing MS better than Roche's Rebif, while also showing efficacy in primary progressive MS. 

By Ned Pagliarulo • Sept. 14, 2016

Foamix shares bubble up on Phase 2 data

A topical minocycline foam developed by the specialty pharma helped control rosacea symptoms. 

By Suzanne Elvidge • Sept. 14, 2016

PhRMA highlights industry's autoimmune drug pipeline

A new report from the industry association touts the 300+ drug pipeline, which could bring a wave of new meds to autoimmune disease patients.

By Suzanne Elvidge • Sept. 14, 2016

How to expedite FDA approvals of orphan drugs

A rare disease drug approval was pushed through with the support of PK models to inform dosing strategies.

Sept. 13, 2016

Aveo halts study of lung cancer drug

The Cambridge-based oncology company has struggled to shrug off other troubles tied to its lead candidate, settling fraud charges with the SEC in March. 

By Ned Pagliarulo • Sept. 12, 2016

AstraZeneca searches for differentiator in diabetes market

The big pharma begins multiple outcomes studies for its type 2 diabetes drug. 

By Lisa LaMotta • Sept. 12, 2016

Lexicon, Sanofi tout positive T1 diabetes data

The pair announced strong results in Phase 3 for an SGLT2 inhibitor in type 1 diabetes patients. 

By Lisa LaMotta • Sept. 9, 2016

J&J pushes forward with hep C triple-combo

Interim results released Friday by J&J partner Achillion showed promise for treating the liver disease in a shorter time period than existing options.

By Ned Pagliarulo • Sept. 9, 2016

Repros climbs on Phase 2 data

Results from an ongoing trial showed Repros' endometriosis drug cut pain pill use by half in women with moderate to severe endometriosis. 

By Suzanne Elvidge • Sept. 8, 2016

Bluebird proceeds with late-stage trial after key improvement

Shares of Bluebird moved higher on news the Cambridge-based biotech would be able to proceed with an improved manufacturing process in its Phase 3 trial. 

By Ned Pagliarulo • Sept. 8, 2016

Tonix shelves fibromyalgia plans after Phase 3 miss

While the fibromyalgia program will be discontinued, Tonix hopes to move ahead with clinical development of TNX-102 in PTSD. 

By Ned Pagliarulo • Sept. 7, 2016

CoLucid gets boost from Phase 3 migraine results

The Cambridge, MA-based biopharma hopes its drug can be an effective treatment option for patients with cardiovascular risk factors. 

By Suzanne Elvidge • Sept. 7, 2016

AstraZeneca makes a play for asthma market with positive data

Benralizumab could cut hospitalizations with every-other-month dosing and make the big pharma competitive in the space. 

By Suzanne Elvidge • Sept. 6, 2016

Merck ditches long-troubled bone drug

The big pharma has finally scrapped development of its beleaguered osteoporosis drug after several years of delays. 

By Lisa LaMotta • Sept. 2, 2016

Momenta pulls the plug on pancreatic cancer drug

Enrollment in a Phase 2 trial testing necuparanib was halted earlier this month. Now the biotech is discontinuing the program altogether. 

By Ned Pagliarulo • Sept. 2, 2016

MedCo holds out for full analysis of cholesterol data

Medicine Company’s cholesterol drug interim data was 'inconclusive' and the company is waiting on the final trial results. 

By Suzanne Elvidge • Sept. 1, 2016

Roche's Tecentriq ready to compete in lung cancer

But stiff competition looms: Bristol-Myers' Opdivo and Merck's Keytruda have already staked out a significant lead in the red-hot immuno-oncology market. 

By Ned Pagliarulo • Sept. 1, 2016

Tonix preps to enter PTSD market

The biotech cleared Phase 2 and is readying its lead compound for late-stage trials.

By Lisa LaMotta • Aug. 31, 2016

CTI gets mixed data, but hold stands

Shares of the Seattle-based biotech jumped on the news, but development is still shadowed by a full clinical hold placed on the drug by the FDA in February. 

By Lisa LaMotta • Aug. 30, 2016