Halozyme unveils mid-stage data for pancreatic cancer drug

The cancer-focused biotech said its drug has an edge in progression-free-survival, though some remain skeptical.

By Jacob Bell • Jan. 5, 2017

Ocular boasts more positive data for Dextenza

The company intends to release safety data and submit the post-surgery eye inflammation drug for approval in early 2017.

By Jacob Bell • Jan. 5, 2017

Explore the Trendline➔

Oncology's research boom

More than one quarter of the medcines cleared by the FDA's main review office since 2015 have been cancer drugs, a tally that reflects the advent of cancer immunotherapy as well as continued progress in matching treatment to genetics.

By BioPharma Dive staff

Inotek shares freefall after glaucoma drug failure

The Lexington, MA-based company's shares were 71% lower on Tuesday than when the markets closed on Dec. 30.

By Jacob Bell • Jan. 4, 2017

Newron sees promise in schizophrenia drug

Preliminary Phase 2a results showed the drug was generally well-tolerated, leading the company to believe further testing is warranted.

By Suzanne Elvidge • Jan. 4, 2017

As R&D returns take a hit, some pharmas are ramping up spending

BioPharma Dive will be publishing several articles in the coming weeks taking a look at the numbers behind R&D spending and drug revenues. 

By Ned Pagliarulo • Dec. 24, 2016

Prescribed Reading: An uptick in year-end M&A

Several companies are striking deals to round out the year, while others are trying to bury bad data, and the FDA cracks down on manufacturing. 

By Lisa LaMotta • Dec. 23, 2016

Roche hemophilia drug hits mark in Phase 3

The Swiss pharma also offered up more details on four adverse events which had sparked concerns about the drug's prospects last month. 

By Suzanne Elvidge • Dec. 23, 2016

Roche touts efficacy of MS drug despite delays

More complete data on the safety and efficacy of Ocrevus was published this week in The New England Journal of Medicine. 

By Suzanne Elvidge • Dec. 23, 2016

Alexion fails to PROTECT Soliris franchise

A trial failure for the blockbuster drug adds to the string of bad news for the company. 

By Lisa LaMotta • Dec. 22, 2016

Acadia claims Alzheimer's success

The company is pushing ahead into Phase 3 trials, despite skepticism. 

By Suzanne Elvidge • Dec. 21, 2016

Prescribed Reading: Bad behavior abounds in biopharma

Charges have come down in a generics price-fixing investigation, while Ophthotech reports deep staff cutbacks and the FDA cautions on misleading advertising.

By Lisa LaMotta • Dec. 16, 2016

RespireRx nets mixed results in Phase 2

The New Jersey-based company is developing a treatment for opioid-induced respiratory depression and sleep apnea. 

By Suzanne Elvidge • Dec. 16, 2016

Centrexion osteoarthritis drug hits its mark in Phase 2

The announcement closes out an active year for the company, which has been working to establish itself in the pain medication space.

By Jacob Bell • Dec. 13, 2016

Achaogen's stocks fly high on antibiotic clinical success

Shares in the biopharma spiked after news its drug plazomicin beat out the last-resort antibiotic colistin in treating complex infections.

By Suzanne Elvidge • Dec. 13, 2016

Armed with IPO cash, CRISPR biotechs grow gene-editing tech

Even as a high-stakes patent battle steals headlines, the three CRISPR biotechs which IPO'd this year are busy building momentum. 

By Ned Pagliarulo • Dec. 12, 2016

Novartis, Ophthotech combo therapy fails in Phase 3

The clinical results effectively sideline a potential competitor to Regeneron's blockbuster drug Eylea.

By Jacob Bell • Dec. 12, 2016

Prescribed Reading: Cures for pharma funding

Cures provides funding for pharma research, while AstraZeneca and Lilly continue their pursuit of an Azheimer's treatment, and CAR-Ts wow at ASH. 

By Lisa LaMotta • Dec. 9, 2016

Valeant upbeat on Phase 3 success for psoriasis drug

Yet a crushing debt burden and floundering efforts to sell off assets has limited investor confidence in the company's new look. 

By Suzanne Elvidge • Dec. 9, 2016

Biogen boosted by early Alzheimer's data

In the wake of Eli Lilly's high-profile solanezumab miss, attention has shifted to Biogen's aducanumab as the most promising Alzheimer's candidate. 

By Ned Pagliarulo • Dec. 9, 2016

Horizon tanks on Phase 3 failure

The specialty pharma is pulling out of its Friedreich's ataxia program after the drug missed its primary and secondary endpoints in the study. 

By Lisa LaMotta • Dec. 8, 2016

AbbVie breast cancer drug falls short in Phase 2

A larger, pivotal Phase 3 study of the PARP inhibitor will be the real test for the drug's potential in BRCA-mutated breast cancer. 

By Ned Pagliarulo • Dec. 7, 2016

ASH: I/O drugs pushing into blood cancers

Merck & BMS trumpeted CHL results for Keytruda and Opdivo/Adcetris as part of their aim to move beyond solid tumors.

By Suzanne Elvidge • Dec. 7, 2016

ADCs: A booming field for new cancer-fighting therapies

Tens of thousands of patients already use the two marketed antibody-drug conjugate products, and the pipeline is brimming with second-generation offerings. 

By Judy Packer-Tursman • Dec. 7, 2016

5 biggest Alzheimer's trial setbacks

In the wake of the latest Alzheimer's drug failure, BioPharma Dive revisited a therapeutic field littered with failures. 

By Lisa LaMotta • Dec. 7, 2016

AstraZeneca touts Tagrisso's edge in lung cancer

Results showed the drug extended progression-free survival by a median of 6 months compared to standard chemotherapy.  

By Jacob Bell • Dec. 6, 2016