Clinical Trials: Page 139
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Study: Partial stem-cell transplant reverses sickle cell disease
The study, published Wednesday in the Journal of the American Medical Association, suggests a major shift in treatment.
By Nicole Gray • July 2, 2014 -
GSK/Theravance apply for U.S. approval of once-daily asthma treatment
This two-drug, fixed-combo is designed to be used in various pulmonary conditions.
By Nicole Gray • July 1, 2014 -
Explore the Trendline➔
National Institutes of Allergy and Infectious Diseases. (2016). "Human natural killer cell" [Micrograph]. Retrieved from Flickr.
TrendlineCell therapy
The continued emergence of CAR-T therapy has fueled research into next-generation approaches and new applications, such as its use in autoimmune diseases.
By BioPharma Dive staff -
Lundbeck's stroke drug fails in advanced clinical trials
There was no statistically significant difference between placebo-treated patients and patients treated with drug.
By Nicole Gray • June 30, 2014 -
NICE changes its position on Glivec use
The agency is liberalizing its previous stance even though the drug costs more than $35,000 per year.
By Nicole Gray • June 30, 2014 -
Viiv's HIV combo drug recommended for approval by EMA advisers
It's likely the drug will become a formidable competitor to Gilead's Atripla.
By Nicole Gray • June 30, 2014 -
EU advisors recommend Avastin for refractory ovarian cancer
The drug will be used in combination with chemotherapy to improve outcomes.
By Nicole Gray • June 27, 2014 -
Boehringer's Pradaxa reversal drug gets breakthrough therapy status
The ability to reverse anticoagulation could help Pradaxa become the leading anticoagulant.
By Nicole Gray • June 27, 2014 -
Eisai files NDA for lenvatinib in Japan
Thyroid cancer affects up to 29,000 people in Japan.
By Nicole Gray • June 27, 2014 -
NICE recommends Invokana for diabetes
This is the 10th drug that NICE has recommended for treatment of type 2 diabetes.
By Nicole Gray • June 26, 2014 -
FDA
FDA requests additional information on AstraZeneca's ovarian cancer drug
The agency has concerns related to efficacy and safety.
By Nicole Gray • June 26, 2014 -
High-dose liraglutide may be the next weight-loss breakthrough
It decreases risk of progression to diabetes in individuals with pre-diabetes.
By Nicole Gray • June 26, 2014 -
Melanoma drug trial stopped early after positive results
The decision could cheer Bristol-Myers Squibb stockholders -- and the medical community.
By Nicole Gray • June 25, 2014 -
EMA grants orphan drug status to multiple myeloma treatment
Marizomib now has orphan drug status in the EU and the US.
By Nicole Gray • June 25, 2014 -
Roche applies for IND for idiopathic pulmonary fibrosis treatment
Erivedge was designated a breakthrough therapy for treatment of basal cell carcinoma.
By Nicole Gray • June 25, 2014 -
Bayer, Dimension Therapeutics collaborating on hemophilia A gene therapy
If the treatment makes it to market, it will be a major game-changer for patients.
By Nicole Gray • June 25, 2014 -
Inovio initiates early-stage clinical trials for cervical cancer drug
The candidate is part of the emerging class of immuno-oncologic drugs.
By Nicole Gray • June 25, 2014 -
Study: Heart disease, diabetes patients more likely to stay on statins
The survey also found heavy drinkers were far more likely to stop taking the medication.
By Randy Lilleston • June 24, 2014 -
Kala Pharma advances clinical testing of ocular drug
The nanotechnology-based drug is being evaluated for use in dry eye disease and perisurgical inflammation of the eye.
By Nicole Gray • June 24, 2014 -
MacroGenic moves into phase 1 with new leukemia drug
This first-in-class candidate has a dual mechanism of action.
By Nicole Gray • June 24, 2014 -
Boehringer Ingelheim stops development of hepatitis C drug
The company cites the competitive landscape as the determining factor.
By Nicole Gray • June 24, 2014 -
Sanofi, Merrimack continue development of molecular target found in many cancers
An extensive phase II clinical trial program is underway.
By Nicole Gray • June 22, 2014 -
Companies collaborate to fight multidrug-resistant pathogens
A new diagnostic test is available in Europe and coming to the U.S., but that's just the first step.
By Nicole Gray • June 22, 2014 -
NICE approves Effient for broader use
The product is now acceptable for treatment of many types of acute coronary syndrome.
By Nicole Gray • June 22, 2014 -
Sivextro approved for hard-to-treat skin infections
This is the second drug covered under the FDA's new Qualified Infectious Disease Program designation.
By Nicole Gray • June 22, 2014 -
Deep Dive
Theory can outrun reality on drug approval fast track
The designation can create a buzz that is often not justified.
By Nicole Gray • June 20, 2014
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