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  • Two test tubes pour different-colored liquids into a beaker in an illustration representative of biopharma mergers.
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    Elizabeth Regan/BioPharma Dive
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    Chiesi to buy KalVista in $1.9B deal for rare disease drug

    The acquisition is the fifth of a biotech company so far this week and, according to some Wall Street analysts, proves pharma’s interest in new and emerging oral therapies for hereditary angioedema.

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    Courtesy of Teva Pharmaceutical
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    Brain drug revival

    Teva nabs experimental Tourette drug in $700M Emalex buyout

    A Jefferies analyst argued the deal — Teva’s largest in a decade — “makes sense” given the synergies between Emalex and the pharmaceutical giant’s neurology business. 

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    News roundup

    FDA tests out ‘real-time’ clinical trials; AbbVie closes in on a KRAS biotech

    Through two pioneering studies, Amgen and AstraZeneca will share study data with FDA scientists as it’s accrued. Elsewhere, Lilly inked a gene editing deal and Pfizer reported success for a multiple myeloma drug.

  • People pass an office building with signage spelling Pfizer in New York City.
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    Pfizer deals extend patent life for a top-selling rare disease drug

    Settlements delaying the arrival of generic versions of tafamidis will protect billions in Pfizer revenue and have implications for others, including BridgeBio Pharma and Alnylam. 

  • A flag bearing the words Boehringer Ingelheim flaps in the breeze.
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    Courtesy of Boehringer Ingelheim
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    Obesity drugs

    Boehringer dual-acting obesity shot hits mark in Phase 3 trial

    Survodutide spurred weight loss Wall Street analysts referred to as “Wegovy-like,” and showed signs it might help preserve muscle mass as well.

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    Emerging biotech

    Coultreon banks $125M to support testing of former Galapagos immune drug

    Backed by Novo Holdings, Regeneron’s venture arm and several others, the biotech believes an oral drug licensed from Galapagos might hold potential treating many immunological diseases. 

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    News roundup

    FDA claims Amgen drug data were ‘manipulated’; Erasca slides despite ‘home run’ results

    Tavneos’ original developer hid a study analysis and then altered data, the FDA alleged. Elsewhere, Erasca’s RAS drug was met with skepticism and Rocket Pharma sold a voucher.

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    Veradermics soars on positive data for baldness treatment

    The results could support the first approval in decades for an oral medicine that can treat male pattern baldness, though the therapy will face competition from generics and over-the-counter medications.  

  • Intellia Therapeutics
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    Permission granted by Intellia Therapeutics
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    Gene editing

    Intellia CRISPR drug succeeds in late-stage study against rare swelling disorder

    The findings position Intellia to bring to market the first “in vivo” gene editing medicine, though the therapy’s commercial potential remains the source of intense investor debate.

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    Permission granted by Ajax Therapeutics
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    Lilly to buy startup Ajax in bid for a better JAK drug

    Worth up to $2.3 billion overall, the deal hands Lilly a drug designed to address the weaknesses of a class of medicines used to treat myelofibrosis and other diseases.

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    Getty Images
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    Oruka surges as long-acting psoriasis drug shows early promise

    A therapy that works similarly to AbbVie’s blockbuster Skyrizi appeared more potent in a mid-stage trial and has the potential to be dosed less frequently. 

  • A photo of Sanofi headquarters in Paris, France.
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    Courtesy of Sanofi
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    Sanofi MS drug rejected in US gets an endorsement in Europe

    Tolebrutinib, which the FDA recently turned back due to safety concerns, received a positive recommendation that positions the therapy for its first regulatory approval. 

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    Permission granted by Roche
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    Roche, facing biosimilar threats, puts faith in new cancer and obesity drugs

    On a conference call, executives claimed that a closely watched breast cancer pill and portfolio of weight loss medicines could bank more than $9 billion annually.

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    FDA approves Regeneron’s hearing loss gene therapy

    Otarmeni, now cleared to treat a rare, inherited kind of hearing loss, is the first gene therapy cleared under the FDA’s “national priority” voucher program and will be offered to eligible patients at no cost.

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    News roundup

    Lilly tumbles on Foundayo’s shaky week; FDA to issue vouchers for psychedelics

    Lilly shares dipped, and Novo’s climbed, as Foundayo’s early trajectory diverged from that of oral Wegovy. Elsewhere, Regeneron inked a drug price deal and two companies announced leadership changes.

    Updated April 24, 2026
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    Sanofi posts upbeat sales as R&D pressure builds

    A string of research setbacks have left the pharmaceutical giant at a crossroads just as a new CEO is set to take over. But positive first-quarter earnings provided the company with a needed boost.

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    Permission granted by Hwang lab
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    Revolution drug shows promise in early pancreatic cancer

    The findings build on data suggesting Revolution’s therapy could upend treatment for a notoriously tough-to-treat tumor and generate billions in sales.

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    An ‘AI scientist’ can tackle drug R&D. What does that mean for pharma?

    A new tool is giving researchers a “data center full of genius Ph.D. students in their pocket.”

  • Moderna's headquarters in Cambridge, MA.
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    Maddie Meyer via Getty Images
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    Vaccines

    Moderna, after losing US funding, rebounds to start mRNA bird flu vaccine trial

    A program that got caught up in HHS’ decision to abandon mRNA research was revived by a public-private coalition and is now beginning a large, late-stage test that could support a future approval.

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    News roundup

    Merck adds to pharma’s AI push; Roche details MS drug results

    Merck is making a $1 billion investment in a deal with Google Cloud. Elsewhere, Roche pitched its case for a closely watched multiple sclerosis pill and Arcus and Gilead are ending a yearslong alliance.

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    Permission granted by Serif Biosciences
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    Startup launches

    Serif, Flagship’s latest biotech, aims to make a new kind of genetic medicine

    The startup is developing “modified DNA” therapies it claims can combine the strengths of multiple approaches, from messenger RNA to gene therapy. 

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    AACR 2026: Revolution’s next prospect, Merck’s reveal and a lung cancer battle

    Featured at this year’s meeting on early cancer research were results from an immunotherapy Merck acquired in 2024 and several targeted medicines for lung tumors.

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    Brain drug revival

    Trump executive order lifts psychedelics biotechs

    Meant to speed research and access to psychedelics for mental health conditions, the order is the latest in a series of developments that, to Wall Street, make psychedelics a more “investable space.”

  • A wall showing a Merck & Co. logo in Kenilworth, New Jersey
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    Courtesy of Merck & Co.
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    Merck’s fast-ascending kidney cancer drug hits a setback

    Welireg’s failure in first-line kidney cancer removes a blockbuster opportunity and could leave an opening for a rival drug from Arcus Biosciences, analysts said.

  • A portrait of Jeff Jonas and Al Robichaud.
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    Permission granted by Tortugas Neuroscience
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    Startup launches

    Tortugas debuts with $106M and brain drugs from Hansoh, Eisai

    Led by former Sage Therapeutics executives Jeff Jonas and Al Robichaud, the company is starting out with a portfolio of neurological medicines in clinical testing.