Deep Dive: Page 4

Industry insights from our journalists


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    Novo Nordisk
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    Is the future of diabetes treatment better drugs or better care?

    Drug manufacturers are trying to push the boundaries of glucose control, but cost concerns could rein in ambitions.

    Jonathan Gardner • Sept. 23, 2019
  • Public trust in drugmakers is at an all-time low. Can biopharma recover?

    Leaders are grappling with how to improve the industry's reputation at a time when the broader business world is under increased scrutiny.

    Andrew Dunn • Sept. 11, 2019
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    Amgen
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    Amgen puts its KRAS hopes on 'Navy Seals' team of drug hunters

    Found in many solid tumors, mutant KRAS is cancer research's white whale. Amgen's drug looks the most promising to emerge from decades of failed efforts, but others are close behind. 

    Ned Pagliarulo • Aug. 30, 2019
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    Getty Images
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    Amyloid's last hope? Prevention studies next big test for Alzheimer's research

    The DIAN-TU trial, studying patients genetically predisposed to Alzheimer's, could help decide the fate of what's been the dominant hypothesis of the disease's cause.

    Jonathan Gardner • Aug. 29, 2019
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    Kendall Davis/BioPharma Dive
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    Unblinded: Rebekah Gee's drug pricing experiment in Louisiana

    Louisiana's health secretary negotiated a new payment model with Gilead for one of the poorest states in the country. Could it spread nationwide?

    Andrew Dunn • Aug. 28, 2019
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    Brian Tucker/BioPharma Dive
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    Number of female biotech CEOs remains 'shockingly low,' putting spotlight on BIO

    "I need more from BIO," the group's diversity chair and Halozyme chief Helen Torley told BioPharma Dive. More than 90% of CEOs running the industry's top companies are men.

    Andrew Dunn • July 31, 2019
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    Once 'bodies for hire,' CROs are finding a new role as data specialists

    Drugmakers and regulators are paying more attention to what real-world data can prove — driving demand for CROs to help keep up.

    Jacob Bell • June 28, 2019
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    Kendall Davis/BioPharma Dive
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    Unblinded: Kevin Gorman on Neurocrine's rise, fall and future

    The biotech's share price fell from $70 to $2, and its headcount shrunk by nearly 90%. So how did Neurocrine make it through?

    Andrew Dunn • June 18, 2019
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    Getty / Edited by BioPharma Dive
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    The gene therapy era has arrived. So have the challenges.

    With multiple gene therapies nearing market, the U.S. systems of reimbursement, regulation and research are being put to the test.

    Andrew Dunn • June 7, 2019
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    Brian Tucker/BioPharma Dive
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    Follow the money: How biopharma CEOs and workers got paid in 2018

    Which CEOs made the most? The least? Does biotech pay better than pharma? BioPharma Dive pulled data from hundreds of proxy statements to find out.

    Andrew Dunn • May 28, 2019
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    Yujin Kim/BioPharma Dive
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    No one knows the size of the NASH market

    Industry is still using a broad estimate for the NASH population, which has led to very different views on the size of the potential market opportunity.

    Jacob Bell • May 16, 2019
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    Danielle Ternes/BioPharma Dive
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    On the path to patients, NASH drugs may hit a payer roadblock

    Wall Street estimates and clinical data suggest the earliest NASH drugs could come with limited efficacy but high price tags. Healthcare providers fear that won't sit well with payers.

    Jacob Bell • May 15, 2019
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    Yujin Kim/BioPharma Dive
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    Will a big needle burst the NASH bubble?

    With less invasive tests still a few years off, doctors worry liver biopsies will limit access to the initial wave of NASH drugs — if any make it to market. 

    Jacob Bell • May 14, 2019
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    Novartis
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    Pharma, late to digital game, rushes to catch up

    In the past two years, six of the largest pharmas appointed chief digital or information officers to top management for the first time, a signal of growing industry interest in revamping how it does business.

    Ned Pagliarulo • May 13, 2019
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    Biopharma happily takes the tax cuts, but the jobs are harder to find

    The tax burden of U.S.-based drugmakers shrank by nearly one-quarter following the 2017 Republican tax bill, but jobs edged up only slightly, a BioPharma Dive analysis found.

    Jonathan Gardner • May 9, 2019
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    Kendall Davis/BioPharma Dive
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    Unblinded: Hervé​ Hoppenot on solving Incyte's 'single asset syndrome'

    Last April, a closely watched study of an Incyte cancer drug failed, sending the biotech back to the drawing board. This year could help answer what's next. 

    Ned Pagliarulo • April 10, 2019
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    Aducanumab's failure puts pressure on field to look beyond amyloid

    "At this point, we've done the right experiment and the hypothesis didn't hold true," said Howard Fillit, chief science officer of the Alzheimer’s Drug Discovery Foundation.

    Ned Pagliarulo • March 22, 2019
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    Kendall Davis/BioPharma Dive
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    Unblinded: Scott Gottlieb on biosimilars' precarious moment and the gene therapy boom

    The outgoing FDA chief spoke with BioPharma Dive a day before his surprise resignation, detailing how drugmaker "shenanigans" have evolved and weighing in on gene therapy's inflection point.

    Andrew Dunn • March 12, 2019
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    Brian Tucker/BioPharma Dive
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    Pharma is shuffling around jobs, but a skills gap threatens the process

    Drugmakers have found difficulty luring employees who can work with the latest technologies away from the likes of Amazon and Google, for instance. 

    Jacob Bell • Feb. 4, 2019
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    Kendall Davis/BioPharma Dive
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    A flashy 2019 start to pharma M&A, but will it last?

    Recent high-profile acquisitions don't fully clear up what the buyer's market will look like in an expected bumper year for dealmaking.

    Jacob Bell • Jan. 22, 2019
  • How a 'regulatory dead zone' may be holding up copycat insulin

    The FDA has talked up biosimilars' potential impact on the insulin market, but changing regulations have complicated matters for would-be competitors.

    Andrew Dunn • Jan. 14, 2019
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    Kendall Davis/BioPharma Dive
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    At JPM, the NASH flood gates start to crack

    Multiple late-stage results are slated for 2019, bringing to the forefront a question of how battle lines will be drawn across the market.

    Jacob Bell • Jan. 11, 2019
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    Hunting productivity, drugmakers pitch new 'pillars' of R&D

    By some measures, returns on R&D have fallen to decade lows. Pharmas and biotechs, however, argue new technologies could open faster paths to market. 

    Ned Pagliarulo • Jan. 11, 2019
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    Kendall Davis/BioPharma Dive
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    3 questions leaving ASH

    Like many a medical meeting, ASH showcased data that — while promising — also offers as many questions as answers.

    Jacob Bell • Dec. 5, 2018
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    Jacob Bell/BioPharma Dive
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    At ASH, bispecific cancer therapies make a mark

    The therapies work to guide tumor-fighting immune cells to target cancerous invaders. Research at ASH suggests they could be another avenue of attack in immuno-oncology.

    Ned Pagliarulo and Jacob Bell • Dec. 5, 2018