Biotech: Page 17


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    Padlock investors sue Bristol Myers; Dietmar Berger is Gilead’s new CMO

    Padlock Therapeutics investors accused Bristol Myers of avoiding making milestone payments promised under a 2016 deal. Elsewhere, Gilead CEO Daniel O’Day hired Berger away from Sanofi. 

    By BioPharma Dive staff • Dec. 13, 2024
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    AbbVie to acquire Roche spinout Nimble in immune drug deal

    The pharma will pay $200 million to buy Nimble and a preclinical oral drug that blocks a protein known as IL-23 — the target of AbbVie’s injection Skyrizi.

    By Ned Pagliarulo • Dec. 13, 2024
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    Spencer Platt via Getty Images
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    Trendline

    Emerging biotech

    New biotechs continue to emerge despite a challenging market environment that has forced venture firms to build their drug startups more cautiously.

    By BioPharma Dive staff
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    Permission granted by Editas Medicine
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    Gene editing

    Editas to lay off staff after search for sickle cell partner comes up empty

    The biotech will cut 180 positions, or about two-thirds of its workforce, and discontinue development of its lead drug candidate reni-cel.

    By Ned Pagliarulo • Updated Dec. 13, 2024
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    ‘Research that’s desperately needed’: White House conference spotlights women’s health

    “Sometimes the most under-hyped sectors are the best places to build very large businesses,” said one venture investor who attended Wednesday’s event.

    By Dec. 12, 2024
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    Q32 Bio battered by study failure of immune drug

    Analysts slashed their price targets for the Massachusetts biotech after ‘messy’ trial results in alopecia and eczema.

    By Kristin Jensen • Dec. 11, 2024
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    BenevolentAI restructures; Lilly preps $15B buyback program

    The drug discovery specialist is laying off staff in a pivot that could take it private. Elsewhere, AbbVie reported a second Parkinson’s study success and Biogen hired a new Wall Street whisperer.

    By BioPharma Dive staff • Updated Dec. 17, 2024
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    Chroma, Nvelop merge to marry genetic medicine ‘cargo’ to delivery

    The combined company, which will pair Chroma’s epigenetic editing with Nvelop’s non-viral particles, has raised $75 million from a broad syndicate.

    By , Ned Pagliarulo • Dec. 11, 2024
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    UniQure shares soar on chance of speedy approval for Huntington’s therapy

    The company now says that, during a recent meeting with the FDA, the two parties agreed on some key elements for an accelerated approval application.

    By Dec. 10, 2024
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    Dimension gets $500M to bankroll biotech’s convergence with tech

    The firm’s co-founders claim to be pursuing a “contrarian” approach, building a team versed in both computing and life sciences and concentrating resources on a smaller number of bets.

    By Dec. 9, 2024
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    Sponsored by Greater Phoenix Economic Council (GPEC)

    Why bioscience and healthcare innovators are looking to Phoenix

    When Mayo Clinic was evaluating locations to build a biotechnology innovation hub, the Greater Phoenix region emerged as the ideal option.

    Dec. 9, 2024
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    BioAge shares tumble after decision to halt obesity drug study

    The biotech disclosed Friday plans to terminate a Phase 2 study testing azelaprag with tirzepatide for weight loss following safety concerns.

    By Dec. 7, 2024
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    AstraZeneca, Daiichi build cancer drug case; Amgen invests $1B

    The two partners disclosed study results supporting an approval application for their drug dato-dxd. Elsewhere, Agenus cut spending and the U.S. PTO withdrew a controversial proposed patent rule.

    By BioPharma Dive staff • Dec. 6, 2024
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    Atlas doubles down on ‘disciplined’ biotech investing with latest fundraise

    The venture firm’s “modest” $450 million fund, a lower total than some of its peers recently raised, reflects lessons learned after Atlas grew too quickly, partner Bruce Booth wrote in a blog post.

    By Kristin Jensen • Dec. 5, 2024
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    Courtesy of GSK
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    GSK taps a startup for shot at Alzheimer’s drug

    The collaboration deal, which could be worth hundreds of millions of dollars, is a “pivotal moment” for Muna Therapeutics, a startup that launched less than four years ago.

    By Dec. 5, 2024
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    Nuvig pulls in $161M to make better immune drugs

    The company is developing treatments to rebalance, rather than suppress, immune function in people with inflammatory conditions, starting with an antibody near Phase 2 testing.

    By Dec. 5, 2024
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    Atea plans Phase 3 study for hepatitis C drug after mid-stage results

    The struggling biotech company is looking to break into the lucrative hepatitis C market with the promise of an easier treatment regimen.

    By Kristin Jensen • Dec. 4, 2024
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    Novavax sells Czech plant to Novo; Relay licenses out a cancer drug

    Novo will pay $200 million to gain control of the protein manufacturing factory. Elsewhere, Roivant dropped a drug program and Takeda acquired a blood disease therapy.

    By BioPharma Dive staff • Dec. 4, 2024
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    Antag, a startup backed by Versant and Novo, joins hunt for obesity drug alternatives

    The company, which raised $84 million, sees validation of its GIP-blocking approach to weight loss in Amgen's recent MariTide drug data.

    By Dec. 4, 2024
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    Janux impresses Wall Street with new prostate cancer drug results

    While early and from a small trial, the findings suggest Janux’s method of “masking” T cell engagers could lead to differentiated results, some analysts said.  

    By Dec. 3, 2024
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    Coherus, sharpening immuno-oncology focus, sells another biosimilar for over $500M

    The company reached a deal to divest its third biosimilar this year, selling a copycat version of Amgen’s Neulasta for up to $558 million. 

    By Dec. 3, 2024
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    Novocure device succeeds in pancreatic cancer study; FDA sets Cytokinetics decision date

    Using tumor-treating fields alongside chemotherapy improved patient survival, Novocure said. Elsewhere, Cytokinetics got a key PDUFA date and Fate Therapeutics swapped CEOs.

    By BioPharma Dive staff • Dec. 2, 2024
  • antitrust law, FTC, DOJ, merger review guidelines, Freshfields
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    Pharma hopes Trump will bring change to the FTC. They may be disappointed.

    Some in the drug industry expect more lenient merger enforcement under a second Trump administration. One former regulator argues that might not be the case.

    By Kelly Bilodeau • Nov. 27, 2024
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    Q&A // Brain drug revival

    How Intra-Cellular surprised Wall Street by breaking character

    The biotechnology company, which sees itself as "pretty conservative," recently put out an ambitious long-term revenue forecast for its schizophrenia and depression medicine Caplyta.

    By Nov. 27, 2024
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    Kronos, Idorsia plan layoffs; PTC shelves ALS drug

    Kronos is cutting 83% of its workforce, while Idorsia is considering eliminating as many as 270 jobs. Elsewhere, PTC disclosed negative Phase 2 results for its ALS drug candidate utreloxastat.

    By BioPharma Dive staff • Nov. 27, 2024
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    Biohaven muscle drug misses goal of SMA study, but advances in obesity

    The setback likely removes one competitor to an emerging spinal muscular atrophy medicine from Scholar Rock, but sets the stage for a pair of readouts with implications for weight loss research.

    By Nov. 25, 2024