Biotech: Page 28


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    Viking shares jump on plans to speed obesity drug into late-stage testing

    The drug’s advancement continued what one analyst described as a “torrid” pace for Viking’s closely watched medicine, which started human testing in 2022 and could reach a Phase 3 trial next year.  

    By Kristin Jensen • July 25, 2024
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    Biogen, Sage tremor drug fails key trial

    Known as SAGE-324, the drug was one of the key assets Biogen gained rights to through a billion-dollar research deal inked back in 2020.

    By July 24, 2024
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    Spencer Platt via Getty Images
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    Trendline

    Emerging biotech

    New biotechs continue to emerge despite a challenging market environment that has forced venture firms to build their drug startups more cautiously.

    By BioPharma Dive staff
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    Novartis invests in bispecifics for cancer; Bob Langer steps down from Moderna board

    The Swiss pharma is paying Dren Bio $150 million to partner on “targeted myeloid engagers.” Elsewhere, Geron is losing its commercial chief and Biovectra will sell to Agilent for $925 million.

    By BioPharma Dive staff • July 24, 2024
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    Autobahn raises $100M on investor interest in neuropsych drugs

    Autobahn’s lead candidate is designed to stimulate thyroid hormone receptors as a way to complement existing antidepressants.

    By July 24, 2024
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    Peddalanka Ramesh Babu via Getty Images
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    Startup led by former J&J executives raises $165M for cancer, immune disease drugs

    Peter Lebowitz, who for years led J&J’s oncology R&D, is the CEO of the startup, called Third Arc Bio and launched by Omega Funds in 2022.

    By Ned Pagliarulo • July 23, 2024
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    US government declines to clear Bluebird fertility support for Zynteglo patients

    The Health and Human Services' inspector general issued a "negative opinion" on Bluebird's request one week after Vertex sued the federal government over access to fertility preservation services.

    By Ned Pagliarulo • July 22, 2024
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    Brian Tucker/BioPharma Dive
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    Private biotech M&A surges amid difficult IPO market

    Private biotech company acquisitions are on their fastest pace in years, a trend some in the industry say is driven by the abundance of mature, but not yet public, drug startups. 

    By July 22, 2024
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    Permission granted by InterVenn Biosciences
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    Sponsored by InterVenn Biosciences

    Breakthroughs in immunotherapy: glycoproteins as predictive biomarkers for therapeutic response

    Serum-based glycoproteins demonstrate success in predicting immune checkpoint inhibitor therapy outcomes.

    July 22, 2024
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    Lilly alone in bidding for Morphic; Novartis won’t yet file MorphoSys drug

    Federal filings showed no companies other than Lilly made an offer to buy Morphic, while Novartis executives said they’re still waiting for more data on pelabresib.

    By BioPharma Dive staff • July 19, 2024
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    Immune reset

    Artiva prices $167M IPO, riding optimism for autoimmune cell therapy

    The offering comes days after the publication of a paper showing what analysts said was early proof that “off-the-shelf” cell therapies can treat inflammatory diseases.

    By July 18, 2024
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    Caribou lays off staff; Roche walks away from Relay

    Caribou is slashing its workforce by 12%. Elsewhere, a CDMO is investing in GLP-1 drug demand and Beam’s CFO is returning to J.P. Morgan.

    By BioPharma Dive staff • July 17, 2024
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    NGM, now private, raises $122M for redrawn research plans

    The Series A round was led by healthcare investor The Column Group, which made the 17-year-old biotechnology company private earlier this year.

    By July 17, 2024
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    Cardurion raises another $260M to fuel heart drug pipeline

    The financing, which ranks as one of the year’s larger private rounds, will help the startup advance a pair of drugs and potentially acquire other medicines. 

    By July 16, 2024
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    Courtesy of Vertex Pharmaceuticals
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    Vertex taps Orum to hunt for better ‘preconditioning’ drugs

    The deal gives Vertex rights to use Orum’s ADC-like technology to discover gentler preparatory regimens for patients receiving intensive treatments like Casgevy.

    By July 16, 2024
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    Sionna revives AbbVie’s cystic fibrosis drugs, eyeing a shot at Vertex

    The startup says drugs AbbVie abandoned last year could form a combination regimen with “superior efficacy” to Vertex’s market-leading medicines.

    By July 16, 2024
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    National Institute on Aging. (2017). "Beta-Amyloid Plaques and Tau in the Brain" [Image]. Retrieved from Flickr.
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    Asceneuron raises another $100M for Alzheimer’s drug development

    The Merck KGaA spinout has a tau-regulating medicine it claims could be an “ideal therapy” for Alzheimer’s. The pitch has intrigued both healthcare investors and pharma venture arms.

    By July 16, 2024
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    Revolution Medicines firms up Phase 3 trial plans with latest cancer drug data

    Updated results show the biotech's RAS inhibitor shrank pancreatic tumors in 20% to 25% of study participants, but with high rates of side effects like rash and nausea.

    By Ned Pagliarulo • July 15, 2024
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    Leqembi sales inch higher; Spark’s pivot leads to layoffs

    Sales data suggest forecasts for the Alzheimer’s drug may be in reach. Elsewhere, a well-funded DNA sequencing startup landed one of the year’s larger private funding rounds.  

    By BioPharma Dive staff • July 12, 2024
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    AbbVie names new R&D head; Arcutis eczema cream approved

    Roopal Thakkar will succeed Tom Hudson as AbbVie’s top scientist. Elsewhere, Skyhawk is advancing its Huntington’s drug and Zevra is preparing for an FDA advisory committee meeting.

    By BioPharma Dive staff • July 10, 2024
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    Jerod Harris via Getty Images
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    Flagship raises $3.6B for biotech investing

    The latest round of funding comes as the biotech company creator adds executives and prepares to grow more life sciences startups.

    By Kristin Jensen • July 10, 2024
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    Permission granted by Amylyx Pharmaceuticals
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    Amylyx, with GLP-1 buy, doubles down on blood sugar drugs

    Having recently withdrawn its only product from the market, Amylyx hopes to rebound with a drug that regulates GLP-1 activity and is poised to enter pivotal testing early next year.

    By July 10, 2024
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    SciRhom pulls in $70M for a new type of immune disease drug

    The Series A round will help the startup bring its lead candidate, an antibody aimed at the protein iRhom2, into human testing by the end of 2024.

    By July 9, 2024
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    HilleVax’s norovirus vaccine ineffective in large trial of infants

    Shares in HilleVax plummeted after the company reported its experimental shot failed to meet the primary and secondary goals of the Phase 2b study.

    By July 8, 2024
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    Ligand to buy Apeiron; Roche reports another TIGIT setback

    Acquiring Apeiron will hand Ligand royalty rights on the neuroblastoma drug Qarziba. Elsewhere, CSL reported the first commercial treatment of patients in Europe with its gene therapy Hemgenix.

    By BioPharma Dive staff • July 8, 2024
  • Myricx Bio co-founders Andrew Bell, Roberto Solari and Ed Tate, and CEO Robin Carr in a laboratory.
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    A London biotech raises $114M to hone a new ADC payload

    Myricx Bio is developing a type of payload that it thinks could work in tumors resistant to the toxins contained in ADCs like Enhertu and Trodelvy.

    By July 8, 2024