Biotech: Page 34


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    BioNTech partners with Autolus to boost cell therapy manufacturing

    The German biotech will invest $200 million in Autolus — funds that, along with a $50 million fee, give it licensing options and access to supply infrastructure.

    By Kristin Jensen • Feb. 8, 2024
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    Kyverna IPO adds to biotech momentum with $319M fundraise

    The company, a leading developer of cell therapies for autoimmune diseases, is the fifth drug startup to go public in 2024. All raised at least $100 million. 

    By Feb. 7, 2024
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    Trendline

    Emerging biotech

    New biotechs continue to emerge despite a challenging market environment that has forced venture firms to build their drug startups more cautiously.

    By BioPharma Dive staff
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    BridgeBio sells partial rights to dwarfism drug for $100M

    The deal hands Kyowa Kirin rights in Japan to the drug, which is emerging as a potential rival to BioMarin’s marketed medicine Voxzogo.

    By Feb. 7, 2024
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    Permission granted by Scion Life Sciences
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    Venture firm Scion Life Sciences launches with $310M to back new biotechs

    The new firm intends to carefully select its startups and fund them for the long haul. “We're not a company formation factory,” said co-founder Aaron Kantoff.

    By Feb. 7, 2024
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    Permission granted by Khosla Ventures
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    Q&A

    Khosla Ventures’ Alex Morgan on biotech’s challenges and solving drug delivery

    The life sciences investor has backed a number of startups working on technologies for delivering and manufacturing cell and gene medicines.

    By Feb. 6, 2024
  • Valneva sells regulatory ‘fast pass’ for $103M

    The company said it will invest the sale proceeds into testing of an experimental Lyme disease shot and of Ixchiq, its new chikungunya vaccine.

    By Feb. 5, 2024
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    Arch, a prolific biotech creator, is raising $3B for startup investing

    A regulatory filing shows the firm is putting together a new multibillion-dollar fund, roughly two years after raising a similar amount.

    By Feb. 2, 2024
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    Brain drug developer Alto Neuroscience prices $129M IPO

    The biotech was joined by Fractyl Health in pricing an IPO Thursday evening, adding to last month’s stock offerings from CG Oncology and Arrivent BioPharma.

    By Feb. 2, 2024
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    Avrobio’s road ends in reverse merger with Tim Springer-backed startup

    The gene therapy developer’s demise has given Tectonic Therapeutic, a GPCR-focused startup founded by the prolific biotech entrepreneur, an alternate path to the public markets.

    By Kristin Jensen • Jan. 31, 2024
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    Cour gets $105M, pharma help to ‘reprogram’ autoimmune disease

    Roche, Pfizer and Bristol Myers Squibb have all invested in the startup, which is using nanoparticle technology to retrain the body’s immune system.

    By Jan. 30, 2024
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    Courtesy of Regeneron Pharmaceuticals
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    Regeneron to acquire 2seventy’s cell therapy pipeline

    About 150 of the smaller company's employees will also transition to Regeneron, which is setting up a new cellular medicines research and development unit.

    By Ned Pagliarulo • Jan. 30, 2024
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    Non-opioid drug from Vertex cuts pain in major trial tests

    While the overall results were positive, the drug fell short in both studies on a secondary goal comparing it to a widely prescribed opioid.

    By Ned Pagliarulo • Jan. 30, 2024
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    Deep Dive // State of Play

    CAR-T for lupus: the ‘tip of the iceberg’ for cell therapy in autoimmune disease

    Since a landmark paper in 2022, drugmakers have begun nearly a dozen trials of cell therapies for lupus, with more set to start. Here’s why their efforts are worth watching.

    By Jan. 30, 2024
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    PTC Duchenne drug approval set to be revoked in Europe

    The EMA’s drugs committee again recommended rescinding an OK for Translarna, which was cleared in 2014 despite questions about its benefit.

    By Jan. 26, 2024
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    Cancer drugmaker ArriVent follows on CG’s heels with $175M IPO

    The company is developing an oral alternative to J&J’s lung cancer medicine Rybrevant, and adds to a trend of late-stage drugmakers finding investor demand on Wall Street.

    By Jan. 25, 2024
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    RayzeBio drew other pharma interest before Bristol Myers deal

    Two “global biopharmaceutical companies” made bids to buy the radiopharma specialist, but lost out to Bristol Myers, which negotiated aggressively to secure a $4.1 billion buyout.

    By Ned Pagliarulo • Jan. 25, 2024
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    BenevolentAI appoints former Bayer R&D chief as CEO

    The pharma veteran will take over the AI-focused biotech after a year that included a restructuring, job cuts and the resignation of its CFO. 

    By Kristin Jensen • Jan. 25, 2024
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    CG Oncology prices larger-than-expected $380M IPO in hopeful sign for biotech

    The sector’s first IPO of 2024 could be a positive signal for the handful of other companies that have recently laid out plans for initial public offerings.

    By Jan. 24, 2024
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    Novo strikes another obesity drug deal

    The partnership with startup EraCal Therapeutics, a spinout of Harvard University and Zurich University, adds another prospect to Novo’s pipeline of weight loss drugs. 

    By Kristin Jensen • Jan. 24, 2024
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    Courtesy of Sanofi
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    Sanofi to buy Inhibrx in deal worth up to $2.2B

    The acquisition will give Sanofi an experimental drug for alpha-1 antitrypsin deficiency, while the rest of Inhibrx's assets will be spun into a new company.

    By Ned Pagliarulo • Jan. 23, 2024
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    Pharmas back Accent’s plan to make RNA-targeting cancer drugs

    J&J and Bristol Myers joined the latest funding round for the startup, which was led by the newly launched Mirae Asset Capital Life Science.

    By Jan. 23, 2024
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    Courtesy of Coherus Biosciences
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    Coherus sells Lucentis biosimilar to Sandoz for $170M

    The divestment, which includes sales and reimbursement staff, is part of Coherus’ plan to shift resources toward its R&D work in oncology.

    By Jan. 22, 2024
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    Ionis says rare disease drug succeeds in late-stage HAE study

    The medicine, called donidalorsen, reduced hereditary angioedema-related attacks in the Phase 3 trial. Several competing options to it are already available or in advanced testing, however.

    By Jan. 22, 2024
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    Ikena Oncology to lay off 35% of staff

    The cancer drugmaker is one of about a dozen biotechs that have announced workforce reductions so far in 2024.

    By Jan. 19, 2024
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    A South Korean investment firm starts first US biotech fund

    The $50 million fund, called Mirae Asset Capital Life Science, will back biotechnology companies from seed to Series C rounds.

    By Jan. 18, 2024