Pharma: Page 11
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Courtesy of AbbVie
Brain drug revivalOn Wall Street, ‘flat out’ failure of AbbVie schizophrenia drug leaves analysts stunned
Negative data cost AbbVie billions of dollars in market value and convinced analysts Bristol Myers had placed a better bet in buying Karuna Therapeutics.
By Jacob Bell • Nov. 11, 2024 -
Courtesy of AbbVie
AbbVie’s $9B bet collapses as closely watched schizophrenia drug fails studies
Shares in AbbVie slumped Monday after the company disclosed its psychiatric medicine emraclidine didn’t best placebo in two Phase 2 trials.
By Jacob Bell • Nov. 11, 2024 -
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Looming patent expiries this decade and intensifying competition from China are forcing drugmakers to adapt, while new opportunities open up in oncology and in neuroscience.
By BioPharma Dive staff -
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Tezspire succeeds in chronic rhinosinusitis; Gilead writes down Trodelvy value
AstraZeneca and Amgen's drug could have a new use after positive Phase 3 study results. Elsewhere, Jazz set new plans for a narcolepsy drug and CDMO Avid Bioservices agreed to be taken private.
By BioPharma Dive staff • Nov. 8, 2024 -
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Novo sees Wegovy sales rise as supply constraints ease
Third quarter sales of Novo’s in-demand obesity drug totaled $2.5 billion, roughly 81% higher than the same period in 2023 and nearly doubling the total for Lilly’s Zepbound.
By Jonathan Gardner • Nov. 6, 2024 -
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Moderna said to shuffle sales leadership; Vertex records first Casgevy sale
Stephen Hoge will now oversee vaccine sales at Moderna, per a Bloomberg report. Elsewhere, Intra-Cellular unveiled an ambitious sales target and Syndax inked a lucrative royalty deal.
By BioPharma Dive staff • Nov. 6, 2024 -
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Novo inks Ascendis deal to develop long-acting GLP-1, other metabolic drugs
Per terms, Novo could pay up to $285 million in upfront and milestone fees to Ascendis, which specializes in a kind of drug-enhancing technology.
By Jonathan Gardner • Nov. 4, 2024 -
Daniel Tadevosyan via Getty Images
Regeneron battles Wall Street uncertainty; Madrigal extends fast launch of MASH drug
Regeneron shares continued to decline on growing concerns about Eylea’s future. Elsewhere, new details emerged about Lundbeck’s Longboard buyout and PTC continued a quixotic quest.
By BioPharma Dive staff • Nov. 1, 2024 -
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New Alzheimer's drugsRoche weighs whether speedy approval path is open for latest Alzheimer’s drug
In an investor presentation, executives hinted at the possibility of seeking an accelerated approval of trontinemab if it can significantly lower levels of amyloid in a Phase 3 trial.
By Jonathan Gardner • Oct. 31, 2024 -
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Novo takes big step toward ending Ozempic, Wegovy shortages
All doses of the two drugs are now listed as available in the U.S., per an FDA database, although the company cautioned patients may still experience "variability" filling their prescriptions.
By Ned Pagliarulo • Updated Oct. 30, 2024 -
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GSK vaccine sales sink on lower demand for RSV, shingles shots
The British pharma’s experience during the third quarter mirrored that of rival Pfizer, which also reported lower sales of its competing RSV shot.
By Delilah Alvarado • Oct. 30, 2024 -
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Lilly shares fall as obesity drug sales miss forecasts
Third quarter Mounjaro and Zepbound sales, while up substantially versus the same period last year, grew little compared to the second quarter as wholesalers bought less supply.
By Ned Pagliarulo • Updated Oct. 30, 2024 -
Jeenah Moon via Getty Images
Pfizer sales of RSV vaccine ebb, but company gains market share
New guidelines and the timing of COVID vaccinations impacted uptake of Abrysvo this year, according to a company executive.
By Delilah Alvarado • Oct. 29, 2024 -
Leon Neal via Getty Images
GSK to pay $300M to license drug it sees as potential lupus treatment
The deal with China’s Chimagen Biosciences is the latest example of pharma interest in exploring the potential of “T cell engagers” in autoimmune disease.
By Ned Pagliarulo • Oct. 29, 2024 -
Daniel Tadevosyan via Getty Images
Biogen refreshes its C-suite; Novartis writes down MorphoSys assets
Daniel Quirk, an immunology and neuroscience executive at Bristol Myers Squibb, will be Biogen’s next chief medical officer. Meanwhile, Robin Kramer will replace retiring CFO Michael McDonnell.
By BioPharma Dive staff • Oct. 29, 2024 -
Permission granted by Pfizer
Pfizer answers Starboard challenge with beat-and-raise quarter
Company CEO Albert Bourla said Pfizer would consider “any good ideas” that create value, but argued it has already made important changes to improve the business.
By Ned Pagliarulo • Updated Oct. 29, 2024 -
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Sponsored by FedEx OfficeHow pharmaceutical companies can leverage print to remain agile and competitive
Learn why print remains a preferred channel for healthcare communications, and how printed materials can help build relationships with patients, develop brand loyalty and maintain brand consistency.
Oct. 28, 2024 -
Courtesy of Sanofi
Sanofi earnings boosted by Beyfortus, earlier vaccine sales
Sanofi and partner AstraZeneca recently increased production capacity for their RSV antibody shot, sales of which jumped during the third quarter.
By Delilah Alvarado • Oct. 25, 2024 -
Daniel Tadevosyan via Getty Images
GSK invests $800M in manufacturing; Amgen sets small discount for Eylea biosimilar
The British pharma is making what it calls its largest U.S. manufacturing investment. Elsewhere, Roche and Dyno expanded their alliance to create better viral vectors for use in gene therapy.
By BioPharma Dive staff • Oct. 25, 2024 -
Kevin C. Cox via Getty Images
Merck, Pfizer lifted as CDC backs broader use of pneumococcal vaccines
An agency panel recommended lowering the age for routine vaccination from 65 to 50, boosting the revenue outlook for multiple shots on the market and in development.
By Delilah Alvarado • Oct. 24, 2024 -
Buda Mendes via Getty Images
Dengue is spreading and Sanofi is pulling the US market’s only vaccine. What’s next?
As Sanofi prepares to halt U.S. marketing of its dengue vaccine in 2026, locally acquired infections in the country are raising alarms.
By Alexandra Pecci • Oct. 24, 2024 -
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Q&A // Emerging biotechJ&J’s Asish Xavier on biotech’s rebound in a volatile era
Xavier, who leads biotech venture investing for the big drugmaker, expects an uptick in IPOs as well as renewed interest in the newer crop of gene and cell therapy companies.
By Gwendolyn Wu • Oct. 24, 2024 -
Daniel Tadevosyan via Getty Images
Merck acquires cancer drug startup; Elevidys ex-US sales rise
Yale spinout Modifi agreed to sell to Merck for $30 million upfront. Elsewhere, Sangamo plotted a much faster path to market for its Fabry gene therapy.
By BioPharma Dive staff • Oct. 23, 2024 -
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Starboard makes case for change at Pfizer, citing research, M&A missteps
The activist investor claims Pfizer failed to capitalize on the windfall earned from its COVID-19 vaccine and, in the process, destroyed tens of billions of dollars in market value.
By Ned Pagliarulo • Oct. 22, 2024 -
Courtesy of Sanofi
Sanofi moves ahead with CD&R deal for stake in consumer business
Under the proposed deal, the PE firm would take a controlling 50% stake in Sanofi’s Opella unit, with state-owned Bpifrance taking a minority 2% position.
By Delilah Alvarado • Oct. 21, 2024 -
Courtesy of Novo Nordisk
Oral version of Novo diabetes drug protects heart health in large study
The medicine, which Novo sells as Rybelsus, cut the risk of cardiovascular complications by 14% when added to standard therapies in people with diabetes and heart disease.
By Jonathan Gardner • Oct. 21, 2024
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