Pharma: Page 2
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AstraZeneca, Oxford vaccine prevents COVID-19, though study results raise questions
Data from two late-stage trials showed the shot to be, on average, 70% effective against COVID-19 — an encouraging finding. The lower dose tested, however, unexpectedly outperformed a higher dose.
By Ben Fidler • UPDATED: Nov. 23, 2020 at 10:20 a.m. -
WHO recommends against Gilead's Veklury, in break with US guidelines
The organization argues there's no evidence the antiviral saves lives or improves outcomes for COVID-19 patients, despite positive data on the latter point from a key U.S. study.
By Jonathan Gardner • Nov. 20, 2020 -
Explore the Trendline➔
National Institute of Allergy and Infectious Diseases. (2020). "Novel Coronavirus SARS-CoV-2" [Micrograph]. Retrieved from Flickr.TrendlineInside the global race for a coronavirus vaccine
Some 29 vaccine candidates are now in clinical studies. Early results from five leading efforts are encouraging, suggesting researchers are on the right track despite rapid acceleration of testing.
By BioPharma Dive staff -
Lilly dives into gene editing
Through a deal with Precision Biosciences, the pharma aims to develop therapies for genetic disorders, including Duchenne muscular dystrophy.
By Jacob Bell • Nov. 20, 2020 -
Deep Dive
Hospitals scramble to get ready for coronavirus vaccines
Facilities are preparing ultra-cold storage capabilities and reviewing security plans as they brace for their role in distributing potentially multiple shots.
By Shannon Muchmore • Nov. 19, 2020 -
New AstraZeneca data offer latest hint coronavirus vaccines may protect elderly
Results published Thursday add to hopes the experimental shots now in testing won't only work for young, healthy people. More details are needed, though.
By Ben Fidler • Nov. 19, 2020 -
Pfizer strikes a deal with newly formed China biotech
The deal, which has Pfizer paying as much as $70 million, is the latest in a series of moves by big pharma companies to forge a stronger position in the world's second-largest drug market.
By Kristin Jensen • Nov. 19, 2020 -
New coronavirus vaccine data bolster Pfizer, BioNTech claims of strongly effective shot
Reaching the main goal of their large trial, Pfizer and BioNTech reported 162 cases of COVID-19 among participants who received a placebo, and just eight for those who were vaccinated.
By Ned Pagliarulo • Nov. 18, 2020 -
FDA delays decision on Bristol Myers cell therapy, putting Celgene deal payouts in jeopardy
Travel restrictions have made it difficult for the regulator to inspect a plant used to make the treatment, meaning the drugmaker could miss a deadline critical to former Celgene shareholders.
By Jonathan Gardner • Nov. 17, 2020 -
Moderna's vaccine can last for weeks in a refrigerator, expanding an edge on rivals
Pharmacies and doctor's offices should be able to store Moderna's shot on site, a crucial advantage for the mass immunization challenge that lies ahead.
By Jonathan Gardner • Nov. 16, 2020 -
Lilly backs a biotech's spinout and places a small bet on protein degradation
An alliance with BeyondSpring spinout Seed Therapeutics makes Eli Lilly the latest pharma company to dive into the fast-emerging drug research field.
By Ben Fidler • Nov. 13, 2020 -
AstraZeneca cancer drug found ineffective for COVID-19
The setback follows disappointing results from companies like Novartis and Sanofi, which have also sought to repurpose existing drugs for COVID-19.
By Kristin Jensen • Nov. 12, 2020 -
Pfizer, with vaccine results positive, readies plans to ship coronavirus shot
Twelve trucks and 20 planes would be used each day to distribute the vaccine, should approvals follow Pfizer and partner BioNTech's positive study results.
By Matt Leonard • Nov. 11, 2020 -
Sponsored by IQVIA
Finding the right mix: Digital transformation offers opportunities for improved HCP engagement
Field teams and HCPs alike are learning how digital, data-driven approaches can best support safe, productive engagement.
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Novartis rare disease drug, repurposed for COVID-19, fails in late-stage study
The Swiss drugmaker's COVID-19 research efforts now largely rest on the outcome of a recent alliance to develop oral medicines for the new coronavirus.
By Ben Fidler • Nov. 06, 2020 -
Who would get Regeneron's COVID-19 antibody treatment?
The drug, now being considered for emergency clearance by the FDA, seems to work best in patients whose immune systems haven't responded to infection. Fast antibody testing, however, is spotty.
By Jonathan Gardner • Nov. 05, 2020 -
Merck to pay almost $3B for VelosBio, broadening antibody cancer drug push
Buying VelosBio is Merck's second investment in so-called antibody-drug conjugates since September, reflecting the drug class' fast turnaround.
By Ben Fidler • Nov. 05, 2020 -
Bristol Myers bet pays off as psoriasis drug beats Amgen rival in study
While full data were not disclosed, the trial's outcome signals competition for Amgen's Otezla, which Celgene was forced to divest last year as a result of its acquisition by Bristol Myers.
By Ned Pagliarulo • Nov. 03, 2020 -
US to pay Lilly $375M for supply of COVID-19 drug
Lilly has asked the FDA for emergency approval of the antibody-based treatment, but scaling up production will take time.
By Ned Pagliarulo • Oct. 28, 2020 -
Sanofi, GSK pledge 200M doses to an international coronavirus vaccine alliance
The two drugmakers are aiding an international effort to ensure low- and middle-income countries can get access to successful coronavirus shots.
By Kristin Jensen • Oct. 28, 2020 -
National Institute of Allergy and Infectious Diseases. (2020). "Novel Coronavirus SARS-CoV-2" [Micrograph]. Retrieved from Flickr.
Lilly antibody drug doesn't help hospitalized COVID-19 patients in NIH study
The results could raise doubts about the ability of synthetic antibody drugs to help patients already very sick with COVID-19.
By Ben Fidler • UPDATED: Oct. 27, 2020 at 11:45 a.m. -
Sponsored by SAP
Regulatory-driven material control with SAP
Learn about material segmentation, a unique approach for characteristics-based planning and execution.
By Stephen Cloughley, Senior Director, SAP Life Sciences IBU • Oct. 26, 2020 -
Purdue, reaching $8B settlement with US, pleads guilty to charges over opioid sales
Under a deal reached with the Department of Justice, Purdue faces fines and a forfeiture worth more than $5 billion — the largest penalties ever for a drug company.
By Jacob Bell • Oct. 21, 2020 -
Sponsored by ZS
Patients and physicians brace for flu season amid COVID-19
ZS surveyed more than 500 patients and 500 physicians to gather their perspectives on COVID-19's potential impact on flu vaccination rates.
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National Institute of Allergy and Infectious Diseases. (2020). "Novel Coronavirus SARS-CoV-2" [Micrograph]. Retrieved from Flickr.
J&J halts studies of coronavirus vaccine due to participant's illness
The company did not disclose details, nor could it confirm whether the participant had received its shot. But J&J is now the second vaccine developer, along with AstraZeneca, to suspend testing for a safety review.
By Ned Pagliarulo • UPDATED: Oct. 13, 2020 at 11:15 a.m. -
Mallinckrodt, beset by opioid drug suits, files for bankruptcy
The drugmaker aims to resolve billions of dollars in opioid-related claims and a federal lawsuit over Medicaid rebates, liabilities it says would be "otherwise unmanageable."
By Ned Pagliarulo • Oct. 12, 2020