Biotech: Page 69
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Courtesy of AbCellera
Versant partners with AbCellera to arm startups with better antibodies
The companies pitch their collaboration as a way to give young drugmakers backed by Versant a head start. “Our business is advanced by great ideas coming into the funnel,” said AbCellera’s CEO.
By Ned Pagliarulo • July 27, 2022 -
Elizabeth Regan/BioPharma Dive
BridgeBio advances drug for dwarfism after study data
The highest tested dose of BridgeBio’s drug helped the bones of children with achondroplasia grow faster, leading the company to expand study enrollment.
By Ned Pagliarulo • July 26, 2022 -
Explore the Trendline➔
Spencer Platt via Getty Images
TrendlineEmerging biotech
New biotechs continue to emerge despite a challenging market environment that has forced venture firms to build their drug startups more cautiously.
By BioPharma Dive staff -
Permission granted by Seagen
Seagen, Astellas claim positive results in study key to cancer drug's success
The mid-stage trial tested the companies’ drug Padcev with Merck’s Keytruda in first-line bladder cancer. The data are reportedly a factor in Merck’s talks with Seagen over a potential buyout.
By Ned Pagliarulo • July 26, 2022 -
Permission granted by Biogen
FDA, in another test of its flexibility, agrees to review Biogen's closely watched ALS drug
Known as tofersen, the drug failed in the main study being used to support its approval. But an apparent effect on a protein of interest in ALS research has Biogen convinced the treatment will pass muster with regulators.
By Jacob Bell • July 26, 2022 -
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State of PlayEpigenetic editing: a tunable CRISPR alternative
Three startups have recently emerged with plans to edit the epigenome rather than DNA directly. Here’s why that matters and what they aim to do.
By Ben Fidler • July 26, 2022 -
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Deep Dive // Emerging biotech‘Flat is the new up’: After biotech correction, venture investors turn to safer bets
New companies are being built more carefully and platform technologies are less in vouge as the downturn's effects ripple through the private sector.
By Ben Fidler • July 26, 2022 -
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China-based biotech licenses Sanofi's RNA drug technology
The Lilly-backed Rona Therapeutics gains rights to a platform for small interfering RNA, along with a slate of preclinical candidates aimed at targets in the liver and other tissues.
By Ned Pagliarulo • Updated July 25, 2022 -
Courtesy of Astellas
Astellas to bring research units under one roof in new West Coast center
The pharma company plans to spend $70 million on the South San Francisco facility, which will house West Coast employees of Astellas Gene Therapies.
By Ned Pagliarulo • July 22, 2022 -
Assembly Bio scraps hepatitis B drug, cuts staff after clinical setback
Two top executives will depart in a restructuring that will reduce the California biotech’s staff by 30% and prioritize a pair of preclinical research programs.
By Kristin Jensen • July 21, 2022 -
Permission granted by Sekar Kathiresan
Vertex, Verve team up to develop a gene editing drug for liver disease
The deal, which is worth $60 million upfront, broadens Vertex’s reach into gene editing and expands Verve’s research beyond heart disease.
By Ben Fidler • July 20, 2022 -
Permission granted by Biogen
With Aduhelm sidelined, Wall Street turns to Biogen's next Alzheimer's drug
On the company’s latest earnings call, analysts pressed for more details about the drug, called lecanemab, including its odds for approval and how that could reshape Biogen.
By Jacob Bell • July 20, 2022 -
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Inovio to lay off 18% of staff after COVID shot struggles
The cuts are meant to conserve cash as the biotech attempts to position its coronavirus vaccine as a potential booster.
By Kristin Jensen • July 20, 2022 -
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Roche digs deeper into gene therapy for the eye
The Swiss drugmaker, which already owns rights to a marketed gene therapy for inherited vision loss, will work with startup Avista Therapeutics to develop better delivery tools for the complex treatments.
By Jonathan Gardner • July 20, 2022 -
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Biotech downturn hits another startup as Pact Pharma to lay off nearly 100 employees
The cell therapy developer, which was formed in early 2017 by a group that includes Nobel Prize winner David Baltimore, is one of dozens of biotechs to cut staff this year.
By Delilah Alvarado • July 19, 2022 -
FDA approves new vitiligo treatment, bolstering Incyte's dermatology business
The cream, known as Opzelura, is now the only treatment approved in the U.S. to repigment skin in patients with the most common form of vitiligo.
By Jacob Bell • July 19, 2022 -
Alphaspirit/Stock.adobe.com
Sponsored by OM1Finding hard-to-find patients: Integrating real-world data and AI
Better understanding patient cohorts can shed light on outcomes, but what if coding doesn’t exist?
By Joseph Zabinski, PhD Senior Director, AI and Precision Medicine OM1 • July 18, 2022 -
Novo strikes $110M deal for regulatory fast pass
The Danish drugmaker will buy a priority review voucher from Marinus Pharmaceuticals, the latest in a string of similarly priced purchases.
By Ned Pagliarulo • July 15, 2022 -
CytomX lays off staff, joining growing list of biotechs restructuring
A shaky biotech market has forced another drugmaker to adjust, with CytomX revealing plans to reduce its workforce by 40%.
By Delilah Alvarado • July 14, 2022 -
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Atara shares sink after update on multiple sclerosis trial
Much-anticipated interim results from Atara’s Phase 2 study revealed little about the likelihood of the trial’s success, spurring a market sell-off.
By Ned Pagliarulo • July 13, 2022 -
Jonathan Gardner/BioPharma Dive
Agios CEO to step down, handing role to veteran in rare disease drug sales
A former Celgene executive, Jackie Fouse has led Agios since 2019, overseeing its transformation into a company focused solely on uncommon diseases. In August, she will transition to chair its board of directors.
By Jacob Bell • July 12, 2022 -
National Institute of Allergy and Infectious Diseases/NIH. (2019). "Activated Eosinophils" [Micrograph]. Retrieved from Flickr.
Bain Capital backs new biotech startup developing oral asthma drug
Areteia Therapeutics will receive $350 million from Bain and others to advance a drug that was previously licensed to Biogen for testing as an ALS treatment.
By Delilah Alvarado • July 12, 2022 -
National Institute of Allergy and Infectious Diseases. (2020). "Novel Coronavirus SARS-CoV-2" [Micrograph]. Retrieved from Flickr.
Moderna founder launches Apriori with $50M to stay ahead of virus variants
Flagship Pioneering’s latest startup aims to use predictive technology to find “variant-proof” treatments and vaccines for infectious diseases before they might be needed.
By Delilah Alvarado • July 11, 2022 -
Courtesy of Vertex Pharmaceuticals
Vertex acquires another maker of potentially curative diabetes treatments
For $320 million, Vertex said it plans to buy ViaCyte in a deal that would provide “complementary assets, capabilities and technologies” to the ones it picked up through the 2019 acquisition of Semma Therapeutics.
By Jacob Bell • July 11, 2022 -
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Healthcare asset manager Innoviva buys another biotech at a bargain price
Two months after acquiring Entasis Therapeutics, the firm reached a deal to buy La Jolla Pharmaceutical Co. at a fraction of what La Jolla was worth just a few years ago.
By Jonathan Gardner • July 11, 2022 -
National Institute on Aging. (2017). "Beta-Amyloid Plaques and Tau in the Brain" [Image]. Retrieved from Flickr.
AbbVie dials back partnership on experimental Alzheimer's drug
While AbbVie is bailing on one of the two programs it paid Alector $205 million to acquire five years ago, work will continue on the second project. That drug, however, has shown safety signals.
By Jonathan Gardner • July 8, 2022
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