Clinical Trials: Page 15
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ASCO / Nick Agro
ASCO24: Tagrisso in the spotlight, Caribou’s adjustment and Lilly’s KRAS competitor
AstraZeneca’s therapy could see wider use after ASCO data. Elsewhere, Caribou sought to explain an alternative cell therapy strategy that will delay its study plans.
By BioPharma Dive staff • June 3, 2024 -
Spencer Platt via Getty Images
Structure pill leads to competitive weight loss in obesity study
Shares in the company soared by more than 50% as study data showed the pill led to similar levels of weight loss as a rival drug being developed by Eli Lilly.
By Delilah Alvarado • June 3, 2024 -
Explore the Trendline➔
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TrendlineNeuroscience drug development
Enthusiasm is running higher among drugmakers and investors for neuroscience drug development, buoyed by recent approvals of new Alzheimer’s, ALS and depression medicines.
By BioPharma Dive staff -
Menarini Silicon Biosystems
Sponsored by Menarini Silicon BiosystemsA true liquid biopsy hub – Menarini Silicon Biosystem
Liquid biopsy has emerged as a revolutionary tool for clinical trials, offering cellular and cell-free methods that provide valuable insights into disease progression and treatment response.
June 3, 2024 -
ASCO / Nick Agro
GSK builds case for return of multiple myeloma drug Blenrep
Study results showed the antibody-drug conjugate helped stave off disease progression better than a standard treatment. But eye-related side effects remained common.
By Jonathan Gardner • June 2, 2024 -
Jonathan Gardner/BioPharma Dive
AstraZeneca immunotherapy extends survival by two years in rarer type of lung cancer
The findings, from a trial testing Imfinzi in limited-stage small cell lung cancer, could help AstraZeneca expand the drug's use.
By Jonathan Gardner • Updated June 2, 2024 -
Permission granted by Daiichi Sankyo
With new Enhertu data, an ADC could overtake chemo in breast cancer
The results are a step forward for antibody-drug conjugates, which Enhertu makers AstraZeneca and Daiichi Sankyo see replacing chemo in many tumors.
By Ben Fidler • June 2, 2024 -
Justin Sullivan via Getty Images
Gilead’s Trodelvy misses goal in bladder cancer study
Treatment didn’t significantly improve overall survival in the trial, a finding that one analyst described as a “meaningful setback” to Gilead’s oncology pipeline.
By Ned Pagliarulo • May 31, 2024 -
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Novartis study points to larger role for targeted leukemia drug
Results from a trial called ASC4FIRST show Scemblix outperformed Gleevec and other drugs in treating newly diagnosed chronic myeloid leukemia.
By Ned Pagliarulo • Updated June 3, 2024 -
Mario Tama via Getty Images
J&J antidepressant eases symptoms, improves sleep in key trial
The company has put high expectations on the drug, an orexin-2 antagonist called seltorexant, as a cornerstone of its neuropsychiatry pipeline.
By Ned Pagliarulo • May 29, 2024 -
Elizabeth Regan/BioPharma Dive
Insmed shares double as lung drug data convince Wall Street
After reporting positive clinical trial results for its drug brensocatib, Insmed plans to later this year file for U.S. approval in bronchiectasis that’s not associated with cystic fibrosis.
By Ned Pagliarulo • May 28, 2024 -
ASCO / Nick Agro
Certain menopausal hormone therapy could raise ovarian cancer risk, study finds
The findings, from two trials involving thousands of women, could influence guidelines around use of hormonal treatment for menopause symptoms.
By Delilah Alvarado • May 23, 2024 -
ASCO / Nick Agro
ASCO24: An early look at cancer drug study results
Clinical trial abstracts posted Thursday ahead of this year’s ASCO meeting give a peek at anticipated datasets from Immunocore, Merus, J&J and Merck & Co.
By BioPharma Dive staff • Updated May 24, 2024 -
Elizabeth Regan/BioPharma Dive
Dyne shares jump on trial data for muscle disease drugs
Updated study results for the biotech’s medicines for myotonic dystrophy Type 1 and Duchenne muscular dystrophy appeared to impress analysts and investors on Wall Street.
By Ned Pagliarulo • May 20, 2024 -
iStock / Worawut Prasuwan
Sponsored by PanalgoThe ABCs of SDOH: Meaningful strategies to improve patient outcomes
As biopharmaceutical and medical device companies increasingly recognize the impact of SDOH, a question emerges: how can these sponsors effectively integrate SDOH data into clinical trial recruitment and real-world evidence strategies?
By Meg Richards, PhD, MPH, Executive Director, Scientific Strategy at Panalgo, with Andrew Goldstein, VP of Client Partnerships at Panalgo • May 20, 2024 -
Sean Gallup via Getty Images
Detailed trial data show Bayer drug alleviates menopause symptoms
Full study results disclosed ahead of a medical meeting showed elinzanetant consistently reduced the frequency and severity of hot flashes.
By Delilah Alvarado • May 16, 2024 -
Scott Olson via Getty Images
Lilly’s once-weekly insulin matches daily shots in late-stage tests
The results, which showed Lilly’s drug was as effective at controlling blood sugar as standard injections, come as Novo Nordisk seeks approval for a competing once-weekly insulin.
By Ned Pagliarulo • May 16, 2024 -
Courtesy of Roche
Roche keeps pace in obesity drug field with early study data
A drug Roche acquired in a buyout of Carmot Therapeutics and that works similarly to Zepbound helped people lose nearly 19% of their body weight in a Phase 1 trial.
By Jonathan Gardner • May 16, 2024 -
Permission granted by Biogen
ALS drug developmentBiogen, Ionis shelve ALS drug following study failure
While results indicated the drug works as intended, it didn’t have enough of an effect on a protein that’s become integral to many ALS research programs.
By Jacob Bell • May 16, 2024 -
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Novo Holdings buys stake in life sciences tools company; BioMarin lays off 170
The parent of Novo Nordisk is acquiring 60% ownership of Single Use Support, which specializes in handling of advanced therapies. Elsewhere, BioMarin and gene therapy developer Tenaya are cutting jobs.
By Ned Pagliarulo • May 15, 2024 -
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Sponsored by PearsonAcknowledging comorbidities in trial design is essential for successful outcomes
Examine why adaptive trials that consider comorbidities are critical for a successful trial outcome.
May 13, 2024 -
David Dee Delgado via Getty Images
Patient dies in Pfizer study of Duchenne gene therapy
Pfizer said the patient, a young boy who was treated earlier last year, died suddenly from cardiac arrest. The company is working with trial researchers to investigate further.
By Ben Fidler • Updated May 8, 2024 -
Seth Babin/BioPharma Dive
Verve moves forward with backup base editing therapy
Weeks after a safety setback derailed its lead candidate, the company has treated the first participant in a trial of its heart disease treatment Verve-102.
By Ned Pagliarulo • May 7, 2024 -
Shutterstock / Rocketclips, Inc.
Sponsored by Elligo Health ResearchOptimized trials are the easiest way to meet the FDA’s latest diversity requirements
Optimized clinical trials will help sponsors align with new FDORA diversity requirements.
May 6, 2024 -
Mario Tama via Getty Images
Amgen shares soar as executives outline obesity drug push
The company said data for its Wegovy competitor was promising enough to move the drug into late-stage testing, triggering a stock jump that added billions to Amgen’s market value.
By Jonathan Gardner • May 3, 2024 -
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Deep Dive // State of PlayChasing Novo and Lilly: The obesity drugs that could challenge Wegovy and Zepbound
Large and small drugmakers are vying for a piece of what analysts view as one of the biggest market opportunities in the pharma industry's history. Here’s what’s coming next.
By Jonathan Gardner • April 30, 2024
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